The article considers an actual problem of organizing a safe and sustainable urban transport system. We have examined the existing positive global experience in both infrastructural and managerial decisions. Then to assess possible solutions at the stage of infrastructure design, we have developed the simulation micromodels of transport network sections of the medium-sized city (Naberezhnye Chelny) with a rectangular building type. The models make it possible to determine the optimal parameters of the traffic flow, under which pollutant emissions from cars would not lead to high concentrations of pollutants. Also, the model allows to obtain the calculated values of the volume of emissions of pollutants and the parameters of the traffic flow (speed, time of passage of the section, etc.). On specific examples, the proposed method’s effectiveness is shown. Case studies of cities of different sizes and layouts are implementation examples and possible uses proposed by the models. This study has shown the rationality of the suggested solution at the stage of assessing infrastructure projects and choosing the best option for sustainable transport development. The proposed research method is universal and can be applied in any city.

In the last several decades, cardiovascular diseases (CVDs) have emerged as a major hazard to human life and health. Conventional formulations for the treatment of CVD are available, but they are far from ideal because of poor water solubility, limited biological activity, non-targeting, and drug resistance. With the advancement of nanotechnology, a novel drug delivery approach for the treatment of CVDs has emerged: nano-drug delivery systems (NDDSs). NDDSs have shown significant advantages in tackling the difficulties listed above. Cytotoxicity is a difficulty with the use of non-destructive DNA sequences. NDDS categories and targeted tactics were outlined, as well as current research advancements in the diagnosis and treatment of CVDs. It’s possible that gene therapy might be included into nano-carriers in the delivery of cardiovascular medications in the future. In addition, the evaluation addressed the drug’s safety.

Problem: in recent years, new studies have been published on biological effects of strong static magnetic fields and on thermal effects of high-frequency electromagnetic fields as used in magnetic resonance imaging (MRI). Many of these studies have not yet been incorporated into current safety recommendations. Method: scientific publications from 2010 onwards on the biological effects of static and electromagnetic fields of MRI were searched and evaluated. Results: new studies confirm older work that has already described effects of static magnetic fields on sensory organs and the central nervous system accompanied by sensory perception. A new result is the direct effect of Lorentz forces on ionic currents in the semicircular canals of the vestibular organ. Recent studies on thermal effects of radiofrequency fields focused on the development of anatomically realistic body models and more accurate simulation of exposure scenarios. Recommendation for practice: strong static magnetic fields can cause unpleasant perceptions, especially dizziness. In addition, they can impair the performance of the medical personnel and thus potentially endanger patient safety. As a precaution, medical personnel should move slowly in the field gradient. High-frequency electromagnetic fields cause tissues and organs to heat up in patients. This must be taken into account in particular for patients with impaired thermoregulation as well as for pregnant women and newborns; exposure in these cases must be kept as low as possible.