Madura Island, with more than half of its population, are women encountering socio-economic problems, which eventually create high poverty and unemployment rates. However, the Madurese are also well-known for their resiliency and entrepreneurial characteristics. The effort to solve the issues by empowering the community, women in particular, has been taken seriously primarily by entrepreneurs who were born and raised in the community. Therefore, this research aims to gain insight into the current Madurese entrepreneur’s business pattern and their social concerns in order to propose a strategy to increase productivity as an effort to empower women’s communities. The methodology is qualitative research, which collects data using semi-structured interviews with representatives of the Madurese entrepreneurs in four areas of Madura Island. Their responses are then transcripted and coded for content analysis based on the designed themes. The result shows that they recognise and practise the social entrepreneurship (SE) pattern, although they do not understand the term. Subsequently, the technological application for business operations in general is still limited to the usage of digital technology (DT) for marketing and transaction activities, which helps increase business performance or productivity. Hence, the initiation of technosociopreneurship as a strategy to further develop SE activities with the hope of increasing productivity in empowering women’s communities is proposed. Further research development is advised using quantitative methods for generalisable findings.

In the last several decades, cardiovascular diseases (CVDs) have emerged as a major hazard to human life and health. Conventional formulations for the treatment of CVD are available, but they are far from ideal because of poor water solubility, limited biological activity, non-targeting, and drug resistance. With the advancement of nanotechnology, a novel drug delivery approach for the treatment of CVDs has emerged: nano-drug delivery systems (NDDSs). NDDSs have shown significant advantages in tackling the difficulties listed above. Cytotoxicity is a difficulty with the use of non-destructive DNA sequences. NDDS categories and targeted tactics were outlined, as well as current research advancements in the diagnosis and treatment of CVDs. It’s possible that gene therapy might be included into nano-carriers in the delivery of cardiovascular medications in the future. In addition, the evaluation addressed the drug’s safety.

The national park with Chinese characteristics is the highest level of protection of a kind of natural protection, its establishment marks the park will implement the strictest ecological protection means. It is of great value to construct the utilization system of national park resources under the new natural protected area system in the new era to avoid the misunderstanding of “ecological protection only” and explore how to carry out the sustainable utilization of resources in the reform of national park system and mechanism. According to the analytic hierarchy process (AHP) and Delphi method, the evaluation framework, indicators, reference standards and weights of resource utilization under the national park system were determined in combination with the requirements of constructing the protected natural area system and the total value of resource ecosystem services (including harvest value, existence value and future value). Based on the application research of Bawangling zone of Hainan Tropical Rainforest National Park, the optimal resource utilization system in the future was proposed, and two optimization strategies of ecological adjustment of resource utilization system and construction of suitable resource utilization system were put forward.