According to the World Health Organization (WHO), breast cancer is among the most common cancers worldwide. Most of the anticancer agents have been showing a variety of side effects. Recently, bacterial proteins have been investigated as promising anticancer agents. Azurin is a bacterial cupredoxin protein secreted from Pseudomonas aeruginosa and has been reported as a potent multi-targeting anticancer agent, which makes it an appropriate candidate for drug delivery. Azurin may be delivered to cancer cells using different carriers like polymeric micro and nanoparticles. In the present study, azurin was extracted from the bacterial host and loaded into chitosan particles. Then its effect on MCF-7 cell line was investigated. Chitosan-azurin particles were made using the ion gelation method. Results showed that chitosan-azurin particles are about 200 nm, and the loading of the protein in particles did not affect its integrity. The MTT assay showed a significant reduction in cell viability in azurin and chitosan-azurin-treated cells. The toxicity level after 5 days was 63.78% and 82.53% for free azurin and chitosan-azurin-treated cells, respectively. It seems using an appropriate carrier system for anticancer proteins like azurin is a promising tool for developing low side effect anticancer agents.

Although dykes are a predominant and widely distributed phenomenon in S-Algeria, N-Mali and N-Niger, a systematic, standardized inventory of dykes covering these areas has not been published so far. Remote sensing and geo information system (GIS) tools offer an opportunity for such an inventory. This inventory is not only of interest for the mining industry as many dykes are related to mineral occurrence of economic value, but also for hydrogeologic investigations (dykes can form barriers for groundwater flow). Surface-near dykes, major fault zones, volcanic and structural features were digitized based on Landsat 8 and 9, Sentinel 2, Sentinel 1 and ALOS PALSAR data. High resolution images of World Imagery files/ESRI and Bing Maps Aerial/Microsoft were included into the evaluations. More than 14,000 dykes were digitized and analyzed. The evaluations of satellite images allow a geomorphologic differentiation of types of dykes and the description of their characteristics such as dyke swarms or ring dykes. Dykes are tracing zones of weakness like faults and zones with higher geomechanically strain. Dyke density calculations were carried out in ArcGIS to support the detection of dyke concentrations as stress indicator. Thus, when occurring concentrated, they might indicate stressed areas where further magmatic and earthquake activity might potentially happen in future.

With the increasing call for sustainable development, cities’ demand for green innovation has also been growing. However, relatively little research summarizes the influencing factors of urban green innovation. In this study, we conducted a visual analysis of 1193 research articles on green innovation in cities from the Web of Science core database using bibliometrics and visualization analysis. By analyzing co-occurrence, co-citation, and high-frequency keywords in the literature, we explored the current research status and development trends of influencing factors of urban green innovation and summarized the research in this field. The study found that collaboration among authors and institutions in this field needs to be strengthened to a certain extent. In addition, the study identified the research hotspots and frontiers in the field of urban green innovation, including “management”, “diffusion”, “smart city”, “indicator”, “sustainable city”, “governance”, and “environmental regulation”. Among them, “management”, “governance”, “indicator”, and “internet” are the research frontiers in this field, which are expected to have profound impacts on the future development of urban green innovation. The co-citation analysis results found that China has the highest research output in this field, followed by the United States, England, Australia, and Italy. In conclusion, this study uses CiteSpace software to identify important influencing factors and development trends of urban green innovation. Urban green innovation has gradually become a norm for social and collective behavior in the process of concretization, interdisciplinary development, and technological innovation. These findings have important reference value for promoting research and practice of urban green innovation.

Nanomaterials stand as transformative elements across diverse domains, ranging from biotechnology, aircraft, aviation, and space exploration to medicine, health, environmental preservation, resources, energy, and aerospace. This issue, comprising nine original research articles and two insightful reviews, we embark on a journey to unravel the multifaceted uses of nanomaterials, with a special emphasis on their contributions to environmental protection and medicine. Delving into the unique traits of various nanomaterials, our aim is to provide readers with a comprehensive understanding that transcends conventional boundaries, fostering a deeper appreciation for the impact of nanomaterials.

The study focused on investigating the effects of varying levels of HA (HA₁ = 0, HA₂ = 25, HA₃ = 50, HA₄ = 75, and HA₅ = 100) on Red Dragon, Red Prince, and Red Meat varieties of red radish. This analysis aimed to unravel the relationship between different levels of HA and their impact on the growth and productivity of red radish genotypes. The findings revealed that the Red Prince genotype attained the utmost plant height of 24.00 cm, an average of 7.50 leaves per plant, a leaf area of 23.11 cm², a canopy cover of 26.76%, a leaf chlorophyll content of 54.60%, a leaf fresh weight of 41.16 g, a leaf dry weight of 8.20 g, a root length measuring 9.73 cm, a root diameter of 3.19 mm, a root fresh weight of 27.60 g, a root dry weight of 6.75 g, and a remarkable total yield of 17.93 tons per hectare. The implications of this study are poised to benefit farmers within the Dera Ismail Khan Region, specifically in the plain areas of Pakistan, by promoting the cultivation of the Red Prince variety.