The food supply chain in South Africa faces significant challenges related to transparency, traceability, and consumer trust. As concerns about food safety, quality, and sustainability grow, there is an increasing need for innovative solutions to address these issues. Blockchain technology has emerged as a promising tool to enhance transparency and accountability across various industries, including the food sector. This study sought to explore the potential of blockchain technology in revolutionizing through promoting transparency that enable the achievement of sustainable food supply chain infrastructure in South Africa. The study found that blockchain technology used in food supply chain creates an immutable and decentralized ledger of transactions that has the capacity to provide real-time, end-to-end visibility of food products from farm to table. This increased transparency can help mitigate risks associated with food fraud, contamination, and inefficiencies in the supply chain. The study found that blockchain technology can be leveraged to enhance supply chain efficiency and trust among stakeholders. This technology used and/or applied in South Africa can reshape the agricultural sector by improving production and distribution processes. Its integration in the food supply chain infrastructure can equally improve data management and increase transparency between farmers and food suppliers.There is need for policy-makers and scholars in the fields of service delivery and food security to conduct more research in blockchain technology and its roles in creating a more transparent, efficient, and trustworthy food supply chain infractructure that address food supply problems in South Africa. The paper adopted a qualitative methodology to collect data, and document and content analysis techniques were used to interpret collected data. 

Instant and accurate evaluation of drug resistance in tumors before and during chemotherapy is important for patients with advanced colon cancer and is beneficial for prolonging their progression-free survival time. Here, the possible biomarkers that reflect the drug resistance of colon cancer were investigated using proton magnetic resonance spectroscopy (1H-MRS) in vivo. SW480[5-fluorouracil(5-FU)-responsive] and SW480/5-FU (5-FU-resistant) xenograft models were generated and subjected to in vivo 1H-MRS examinations when the maximum tumor diameter reached 1–1.5 cm. The areas under the peaks for metabolites, including choline (Cho), lactate (Lac), glutamine/glutamate (Glx), and myoinositol (Ins)/creatine (Cr) in the tumors, were analyzed between two groups. The resistancerelated protein expression, cell morphology, necrosis, apoptosis, and cell survival of these tumor specimens were assessed. The content for tCho, Lac, Glx, and Ins/Cr in the tumors of the SW480 group was significantly lower than that of the SW480/5-FU group (p < 0.05). While there was no significant difference in the degree of necrosis and apoptosis rate of tumor cells between the two groups (p > 0.05), the tumor cells of the SW480/5-FU showed a higher cell density and larger nuclei. The expression levels of resistance-related proteins (P-gp, MPR1, PKC) in the SW480 group were lower than those in the SW480/5-FU group (p < 0.01). The survival rate of 5-FU-resistant colon cancer cells was significantly higher than that of 5-FUresponsive ones at 5-FU concentrations greater than 2.5 μg/mL (p < 0.05). These results suggest that alterations in tCho, Lac, Glx1, Glx2, and Ins/Cr detected by 1H-MRS may be used for monitoring tumor resistance to 5-FU in vivo.

Distributed Energy Resources (DERs), such as solar photovoltaic (PV) systems, wind turbines, and energy storage systems, offer many benefits, including increased energy efficiency, sustainability, and grid reliability. However, their integration into the smart grid also introduces new vulnerabilities to cyber threats. The smart grid is becoming more digitalized, with advanced technologies like Internet of Things (IoT) devices, communication networks, and automation systems that enable the integration of DER systems. While this enhances grid efficiency and control, it creates more entry points for attackers and thus expands the attack surface for potential cyber threats. Protecting DERs from cyberattacks is crucial to maintaining the overall reliability, security, and privacy of the smart grid. The adopted cybersecurity strategies should not only address current threats but also anticipate future dangers. This requires ongoing risk assessments, staying updated on emerging threats, and being prepared to adapt cybersecurity measures accordingly. This paper highlights some critical points regarding the importance of cybersecurity for Distributed Energy Resources (DERs) and the evolving landscape of the smart grid. This research study shows that there is need for a proactive and adaptable cybersecurity approach that encompasses prevention, detection, response, and recovery to safeguard these critical energy systems against cyber threats, both today and in the future. This work serves as a valuable tool in enhancing the cybersecurity posture of utilities and grid-connected DER owners and operators. It allows them to make informed decisions, protect critical infrastructure, and ensure the reliability and security of grid-connected DER systems in an evolving energy landscape.

The study’s purpose is to evaluate the influence of some factors of the model of planned behavior (TPB) and the perceived academic support of the university on the attitude toward entrepreneurship and entrepreneurial intention of students. The results of Structural Equation Modeling (SEM) linear structural model analysis with primary data collected from 1162 students indicated that entrepreneurial intention is influenced by attitude toward entrepreneurship, subjective norm, perceived educational support, and perceived concept development support. In addition, this study also found the positive influence of perceived educational support, concept development support, and business development support on attitude towards entrepreneurship. Interestingly, the influence of perceived business development support on entrepreneurial intention was rejected, and personal innovativeness is demonstrated to promote an attitude toward entrepreneurship. Notably, this study also highlights the moderating role of personal innovativeness on the relationship between attitude toward entrepreneurship and entrepreneurial intention. Based on these findings, several implications were suggested to researchers, universities, and policymakers.