Recovery and resilience plan (RRP) approved by the European Commission fosters the development of lifelong learning programs to upgrade employees’ skills and knowledge for digital and green transitions. Within higher education, the field of information and communication technology (ICT) is also a priority area, so we compared the demographic variables of students enrolled in formal first-cycle higher education programs in ICT with those enrolled in lifelong ICT programs within the framework of the Advanced Computer Skills project funded by the RRP in Slovenia. The results show that formal first-cycle higher education in the field of ICT remains strongly male-dominated, whereas, among participants in lifelong learning, the percentage of females stands out. Bachelor programs in ICT are primarily enrolled by young people aged up to 24 years, while shorter university-based lifelong learning programs attract mostly older participants with higher completed formal education and from a broader range of prior educational backgrounds. Finally, when all three variables (gender, age and level of prior formal education) are considered, participants in lifelong learning are much more similar to part-time students than full-time bachelor ICT students, although the percentage of men in formal education is still predominant even in part-time studies. The research findings highlight the need for further efforts to offer lifelong learning in ICT to enable individuals to improve their employment prospects, progress in the workplace or even change their field of work.

This study aims to explore the link and match policy through industrial classes and its impact on the competence and employability of Vocational High School (VHS) graduates. The importance of this research is to address the gap between education and industry by assessing the effectiveness of industrial classes in improving the skills and employability of VHS graduates. Horison Industrial Class (HIC) in 4 schools, namely: (1) SMKN 57 Jakarta, 2 batches of Hospitality expertise programs; (2) SMKN 6 Yogyakarta, there are 3 batches of Hospitality expertise programs; (3) SMKN 6 Semarang, there are 2 batches of Hospitality expertise programs; (4) SMKN 2 Semarang. This research emphasizes the important role of industry involvement and commitment in aligning the curriculum with industry needs. The field findings show that the implementation of the link and match policy through industrial classes significantly affects the quality of learning in VHS. The study also highlights the influence of government support and industry associations in ensuring the successful implementation of industrial classes. Student participation in industry classes directly enriches their learning experiences by allowing them to engage in direct practice in a real work environment. These findings can contribute to the implementation of policies and regulations in the field of education, especially in the context of vocational education. The findings of this study can also be applied to vocational students to improve the quality of graduates in order to meet the qualification standards of employees in companies or industries.

Instant and accurate evaluation of drug resistance in tumors before and during chemotherapy is important for patients with advanced colon cancer and is beneficial for prolonging their progression-free survival time. Here, the possible biomarkers that reflect the drug resistance of colon cancer were investigated using proton magnetic resonance spectroscopy (1H-MRS) in vivo. SW480[5-fluorouracil(5-FU)-responsive] and SW480/5-FU (5-FU-resistant) xenograft models were generated and subjected to in vivo 1H-MRS examinations when the maximum tumor diameter reached 1–1.5 cm. The areas under the peaks for metabolites, including choline (Cho), lactate (Lac), glutamine/glutamate (Glx), and myoinositol (Ins)/creatine (Cr) in the tumors, were analyzed between two groups. The resistancerelated protein expression, cell morphology, necrosis, apoptosis, and cell survival of these tumor specimens were assessed. The content for tCho, Lac, Glx, and Ins/Cr in the tumors of the SW480 group was significantly lower than that of the SW480/5-FU group (p < 0.05). While there was no significant difference in the degree of necrosis and apoptosis rate of tumor cells between the two groups (p > 0.05), the tumor cells of the SW480/5-FU showed a higher cell density and larger nuclei. The expression levels of resistance-related proteins (P-gp, MPR1, PKC) in the SW480 group were lower than those in the SW480/5-FU group (p < 0.01). The survival rate of 5-FU-resistant colon cancer cells was significantly higher than that of 5-FUresponsive ones at 5-FU concentrations greater than 2.5 μg/mL (p < 0.05). These results suggest that alterations in tCho, Lac, Glx1, Glx2, and Ins/Cr detected by 1H-MRS may be used for monitoring tumor resistance to 5-FU in vivo.

Distributed Energy Resources (DERs), such as solar photovoltaic (PV) systems, wind turbines, and energy storage systems, offer many benefits, including increased energy efficiency, sustainability, and grid reliability. However, their integration into the smart grid also introduces new vulnerabilities to cyber threats. The smart grid is becoming more digitalized, with advanced technologies like Internet of Things (IoT) devices, communication networks, and automation systems that enable the integration of DER systems. While this enhances grid efficiency and control, it creates more entry points for attackers and thus expands the attack surface for potential cyber threats. Protecting DERs from cyberattacks is crucial to maintaining the overall reliability, security, and privacy of the smart grid. The adopted cybersecurity strategies should not only address current threats but also anticipate future dangers. This requires ongoing risk assessments, staying updated on emerging threats, and being prepared to adapt cybersecurity measures accordingly. This paper highlights some critical points regarding the importance of cybersecurity for Distributed Energy Resources (DERs) and the evolving landscape of the smart grid. This research study shows that there is need for a proactive and adaptable cybersecurity approach that encompasses prevention, detection, response, and recovery to safeguard these critical energy systems against cyber threats, both today and in the future. This work serves as a valuable tool in enhancing the cybersecurity posture of utilities and grid-connected DER owners and operators. It allows them to make informed decisions, protect critical infrastructure, and ensure the reliability and security of grid-connected DER systems in an evolving energy landscape.