Numerical study of subcooled and saturated flow boiling in the curved and helically  coiled tubes in presence of phase change is one of the challenging area of CFD studies. In this paper, the CFD modeling of the nucleate and convective flow boiling in the small helically coiled tube at low vapor quality (up to the 18.93 percent) region is studied. A proper Eulerian-based mathematical model is used for interphase exchange forces and heat transfer between two phases in CFD modeling using Bulk boiling model. The results show that, the inner and the bottom wall of the helically coiled tube have the lowest and the highest heat transfer coefficient, respectively. The effect of change in coil diameter, helical pitch and tube diameter is investigated on the counters of vapor volume fraction. It is seen that at low vapor quality flows, the heat transfer coefficient is enhanced by decreasing in coil diameter, tube diameter and increasing in coil pitch of helically coiled tube. 

Artificial intelligence chatbots can be used to conduct research effectively and efficiently in the fifth industrial revolution. Artificial intelligence chatbots are software applications that utilize artificial intelligence technologies to assist researchers in various aspects of the research process. These chatbots are specifically designed to understand researchers’ inquiries, provide relevant information, and perform tasks related to data collection, analysis, literature review, collaboration, and more. The purpose of this study is to investigate the use of artificial intelligence chatbots for conducting research in the fifth industrial revolution. This qualitative study adopts content analysis as its research methodology, which is grounded in literature review incorporating insights from the researchers’ experiences with utilizing artificial intelligence. The findings reveal that researchers can use artificial intelligence chatbots to produce quality research. Researchers are exposed to various types of artificial intelligence chatbots that can be used to conduct research. Examples are information chatbots, question and answer chatbots, survey chatbots, conversational agents, peer review chatbots, personalised learning chatbots and language translation chatbots. Artificial intelligence chatbots can be used to perform functions such as literature review, data collection, writing assistance and peer review assistance. However, artificial intelligence chatbots can be biased, lack data privacy and security, limited in creativity and critical thinking. Researchers must be transparent and take in consideration issues of informed content and data privacy and security when using artificial intelligence chatbots. The study recommends a framework on artificial intelligence chatbots researchers can use to conduct research in the fifth industrial revolution.

Background: Multiple sclerosis is often a longitudinal disease continuum with an initial relapsing-remitting phase (RRMS) and later secondary progression (SPMS). Most currently approved therapies are not sufficiently effective in SPMS. Early detection of SPMS conversion is therefore critical for therapy selection. Important decision-making tools may include testing of partial cognitive performance and magnetic resonance imaging (MRI). Aim of the work: To demonstrate the importance of cognitive testing and MRI for the prediction and detection of SPMS conversion. Elaboration of strategies for follow-up and therapy management in practice, especially in outpatient care. Material and methods: Review based on an unsystematic literature search. Results: Standardized cognitive testing can be helpful for early SPMS diagnosis and facilitate progression assessment. Annual use of sensitive screening tests such as Symbol Digit Modalities Test (SDMT) and Brief Visual Memory Test-Revised (BVMT-R) or the Brief International Cognitive Assessment for MS (BICAMS) test battery is recommended. Persistent inflammatory activity on MRI in the first three years of disease and the presence of cortical lesions are predictive of SPMS conversion. Standardized MRI monitoring for features of progressive MS can support clinically and neurocognitively based suspicion of SPMS. Discussion: Interdisciplinary care of MS patients by clinically skilled neurologists, supported by neuropsychological testing and MRI, has a high value for SPMS prediction and diagnosis. The latter allows early conversion to appropriate therapies, as SPMS requires different interventions than RRMS. After drug switching, clinical, neuropsychological, and imaging vigilance allows stringent monitoring for neuroinflammatory and degenerative activity as well as treatment complications.

A systemic and synthetic review of the anatomy of the temporomandibular joint in magnetic resonance imaging was developed for its evaluation. The temporomandibular joint is an anatomical structure composed of bones, muscles, ligaments and an articular disc that allows important physiological movements, such as mandibular opening, closing, protrusion, retrusion and lateralization. Magnetic resonance imaging is an imaging technique that does not use ionizing radiation and is more specific for the evaluation and interpretation of soft tissues, due to its high resolution, so it has an important role in the diagnosis of various maxillofacial pathologies, which is why the dentist should have knowledge of the structures and functions of the temporomandibular joint through magnetic resonance imaging. The review demonstrates the importance of magnetic resonance imaging in the study of the anatomy of the temporomandibular joint, in addition to mentioning the advantages provided by this imaging technique such as its good detail of the soft tissues in its different sequences and the non-use of ionizing radiation to obtain its images.

A logistics service company in Batam faces challenges related to warehouse load fulfillment and sorting inaccuracies. This study aims to identify proposed efficiency improvements to the goods distribution system using the cross-docking method. The research method chosen is cross-docking, a technique that eliminates the storage process in the warehouse, thus saving time and cost. The research findings show significant benefits, especially in achieving zero inventory efficiency. Data processing and discussion revealed that efficiencies were apparent by increasing the sorting tables from 1 to 6, with an output of 90,000 kg during aircraft loading and unloading (compared to approximately 77,000 kilograms). This efficiency arises from the larger output of the sorting tables compared to the input, eliminating the need for warehousing and adding ten trucks. As a result, the shipment can be completed in one trip, with no goods stored in the warehouse. The analysis shows that implementing cross-docking in the company increases efficiency in distributing goods to forwarding partners.

Demographic policy is one of the key tasks of almost any state at the present time. It correlates with the solution of pressing problems in the economic and social spheres, directly depends on the state of healthcare, education, migration policy and other factors and directly affects the socio-economic development of both individual regions and the country as a whole. Many Russian and foreign researchers believe that demographic indicators very accurately reflect the socio-economic and political situation of the state. The relevance of the study is due to the fact that for the progressive socio-economic development of any country, positive demographic dynamics are necessary. The main sign of the negative demographic situation that has developed in modern Russia and a number of countries, primarily European, is the growing scale of depopulation (population extinction). The purpose of this work was to analyze the existing demographic policy of Russia and compare demographic trends in Russia and other countries. The work uses methods of statistical data analysis, comparison of statistical indicators of fertility, mortality, natural population decline, migration, marriage rates in Russia and the Republic of Srpska, methods of retrospective analysis, research of the institutional environment created by the action of state and national programs “Demography”, “Providing accessible and comfortable housing and public services for citizens of the Russian Federation”, “Strategy of socio-economic development for the period until 2024”, Presidential decrees, etc. Research has shown that despite measures taken to overcome the demographic crisis, Russia’s population continues to decline. According to the Federal State Statistics Service of the Russian Federation (Rosstat), as of 1 January 2023, 146.45 million people lived in Russia. By 1 January 2046, according to a Rosstat forecast published in October 2023 the country’s population will decrease to 138.77 million people. To solve demographic problems in the Russian Federation, a national project “Demography” was developed and approved. The government has allocated more than 3 trillion rubles for its implementation. However, it is not possible to completely overcome the negative trend. The authors proposed a number of economic and ideological measures within the framework of agglomeration, migration, and family support policies that can be used within the framework of socio-economic development strategies and national programs aimed at overcoming the demographic crisis.