Multiple myeloma (MM) is a hematologic cancer characterized by clonal proliferation of plasma cells within the bone marrow. It is the most serious form of plasma cell dyscrasias, whose complications—hypercalcemia, renal failure, anemia, and lytic bone lesions—are severe and justify the therapeutic management. Imaging of bone lesions is a cardinal element in the diagnosis, staging, study of response to therapy, and prognostic evaluation of patients with MM. Historically, the skeletal radiographic workup (SRW), covering the entire axial skeleton, has been used to detect bone lesions. Over time, new imaging techniques that are more powerful than SRW have been evaluated. Low-dose and whole-body computed tomography (CT) supplants SRW for the detection of bone involvement, but is of limited value in assessing therapeutic response. Bone marrow MRI, initially studying the axial pelvic-spinal skeleton and more recently the whole body, is an attractive alternative. Beyond its non-irradiating character, its sensitivity for the detection of marrow damage, its capacity to evaluate the therapeutic response and its prognostic value has been demonstrated. This well-established technique has been incorporated into disease staging systems by many health systems and scientific authorities. Along with positron emission tomography (PET)-18 fluorodeoxyglucose CT, it constitutes the current imaging of choice for MM. This article illustrates the progress of the MRI technique over the past three decades and situates its role in the management of patients with MM.
The suspicion of mediastinal alterations, always includes in its initial study, the chest radiography. The identification of mediastinal alterations in the X-ray is a priority. The knowledge of the mediastinal references and the identification of their alterations allows the suspicion of a pathology specific to each of the mediastinal spaces. When the semiology of mediastinal lesions, their location and the three most frequent pathologies are taken into account, the possibility of having an etiological diagnosis increases[1]. This is a review article based on a detailed literature search, in which radiological mediastinal references are studied, with emphasis on the epidemiological data of each one of them.
Ecological environment damage events will destroy or damage the balance between animal and plant habitats and ecosystems, and even pose a threat to China’s ecological security. However, at present, there are some problems in the identification and evaluation of forest ecosystem damage, such as imperfect evaluation system, insufficient quantitative evaluation methods, imperfect damage compensation management system, and lack of analysis of the overall damage of the interaction between human activities and forest ecosystem. Based on the damaged object, the system involves a total of four first-class indicators, including physical damage, mental damage, economic forest fruit loss, forest by-products loss, processing and manufacturing loss, forest tourism loss, scientific research literature and history loss, soil conservation loss, water conservation loss, wind prevention and sand fixation loss, carbon fixation and oxygen release loss, atmospheric purification loss. There are 14 secondary indicators of emergency treatment fee and investigation and evaluation fee, as well as 22 tertiary indicators, and the value quantification method of each indicator is clarified by using market value method, alternative cost method, shadow engineering method, recovery cost method and other methods. The article also discusses the management system of forest ecosystem damage from the two aspects of forestry technology department and judicial administration department. The purpose is to provide reference for the quantification and standardization of forest ecosystem damage assessment technology and the improvement of management system.
Based on the collective forest with common use rights, the social-ecological system analysis framework and autonomous governance theory proposed by Elinor Ostrom are introduced in the forest eco-economic system to analyze the interaction logic among the first-level subsystems and the secondary variables of the forest eco-economic system and the variables related to the autonomous governance of the system to explore the synergistic mechanisms affecting the forest eco-economic system. The results show that: in the case of information asymmetry, collective actions of governmental and non-governmental organizations will aggravate the dilemma of forest eco-economic synergistic development; actors extract forest resource units from the forest resource system to achieve economic benefits; and renewable resources of forest ecosystems can be sustained in the long term when the average extraction rate of humans from forest ecosystems does not exceed the average replenishment rate.
Copyright © by EnPress Publisher. All rights reserved.