Protein- and peptide-based medications are recognized for their effectiveness and lower toxicity compared to chemical-based drugs, making them promising therapeutic agents. However, their application has been limited by numerous delivery challenges. Polymeric nanostructures have emerged as effective tools for protein delivery due to their versatility and customizability. Polymers’ inherent adaptability makes them ideal for meeting the specific demands of protein-delivery systems. Various strategies have been employed, such as enzyme inhibitors, absorption enhancers, mucoadhesive polymers, and chemical modifications of proteins or peptides. This study explores the hurdles associated with protein and peptide transport, the use of polymeric nanocarriers (both natural and synthetic) to overcome these challenges, and the techniques for fabricating and characterizing nanoparticles.
Indonesia’s tourism industry has emerged as a strategic sector, contributing to the country’s foreign exchange earnings. Given the prominence of this sector, there is significant potential for further development. Indeed, a mapping study to assess the dissemination of the trend and the potential for further issues to emerge would be highly beneficial. It is encouraging to note that academics have produced substantial literature on the subject, offering insights into its many facets. However, there is still a need for more in-depth analysis to understand the trends and issues currently facing the sector entirely. Consequently, this article examines the core themes in Indonesia’s tourism studies and maps the potential for future research on tourism issues and regulations. To this end, it employs a qualitative, four-year data set (2020–2023) and a SWOT analysis to identify critical aspects of Indonesian tourism issues. The data was collected in three forms: government reports, statistical data, and research articles (n = 252 samples) from the Scopus database. The results demonstrate that the predominant trend in Indonesia’s tourism industry is the widespread embrace of ecotourism at both the local and regional levels. Instead of identifying a limited number of leading destinations, the focus has shifted towards developing tourism villages and multi-stakeholder tourism. The primary concerns are the Indonesian tourism industry’s growth potential and sustainability. The development potential of Indonesian destinations based on SWOT objectives is a crucial aspect, and its score shows that Indonesia’s tourism sector is strategically positioned to take advantage of strengths and opportunities.
Good health and well-being are embedded in the 3rd Goal amongst the UN Sustainable Development Goals. The primary objective of this research was to identify the most critical economic, social, and administrative barriers to implementing the Expanded Program on Immunization (EPI) in the Punjab Province of Pakistan. A sequential exploratory design and case study technique were used, employing both qualitative and quantitative methods. In the first stage, in-depth interviews with 50 key officials were conducted to identify the most critical barriers to the EPI program. A quantitative analysis was then performed based on the results obtained from qualitative analysis, and rank orders of barriers were received from the same health department experts. The results indicate that twenty-eight barriers can cause implementation problems for this program. Still, the ten barriers that gained the maximum hits are the most important barriers, which include Shortage of vaccinators, mismanagement of vaccines’ cold chain, biometric android application, ice-lined refrigerators, communication gap, inadequate legislation of EPI program, capacity building issues with EPI staff, Misconceptions about EPI program, lack of awareness of the parents and community, refusal cases and inadequate cooperation of lady health workers (LHWs). Coordinated efforts of the government and the public are highly recommended to address these barriers.
This study evaluates the influence of quality certificates on sustainable food production in Poland, considering economic, social, and environmental dimensions. Analyzing 25 different certificates, the research explores their criteria, procedures, and costs across various food product categories, including meat, fish, and plant-based products. The study provides a detailed review of certification processes, from initiation to audits and inspections. It identifies both commonalities and differences among certificates, each addressing unique aspects such as environmental impact, worker rights, and product origins. Despite the diversity in standards and procedures, the study underscores the need for standardized international criteria to improve transparency and meet consumer expectations, highlighting the significant role of quality certificates in advancing sustainable food production.
In today’s fast-paced digital world, generative AI, especially OpenAI’s ChatGPT, has become a game-changing technology with significant effects on education. This study examines public sentiment and discourse surrounding ChatGPT’s role in higher education, as reflected on social media platform X (formerly Twitter). Employing a mixed-methods approach, we conducted a thematic analysis using Leximancer and Voyant Tools and sentiment analysis with SentiStrength on a dataset of 18,763 tweets, subsequently narrowed to 5655 through cleaning and preprocessing. Our findings identified five primary themes: Authenticity, Integrity, Creativity, Productivity, and Research. The sentiment analysis revealed that 46.6% of the tweets expressed positive sentiment, 38.5% were neutral, and 14.8% were negative. The results highlight a general openness to integrating AI in educational contexts, tempered by concerns about academic integrity and ethical considerations. This study underscores the need for ongoing dialogue and ethical frameworks to responsibly navigate AI’s incorporation into education. The insights gained provide a foundation for future research and policy-making, aiming to enhance learning outcomes while safeguarding academic values. Limitations include the focus on English-language tweets, suggesting future research should encompass a broader linguistic and platform scope to capture diverse global perspectives.
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