Dushan county, Guizhou province, is located in the southernmost tip of Guizhou province. It belongs to the temperate climate of the subtropical region and is one of the centers of the karst east Asia area. The total area of the county is 242220 hectares, of which 169142 hectares are rocky desertifi cation or endangered desertification state. At present, the problem of rocky desertification has seriously affected the ecological environment of the county, which is one of the important factors that restrict the local social living standard and economic development. Therefore, it is of great significance to promote the social and economic development of the county by investigating and analyzing the spatial differentiation rules, present situation and harm of rocky desertification in Dushan county.

According to the World Health Organization (WHO), breast cancer is among the most common cancers worldwide. Most of the anticancer agents have been showing a variety of side effects. Recently, bacterial proteins have been investigated as promising anticancer agents. Azurin is a bacterial cupredoxin protein secreted from Pseudomonas aeruginosa and has been reported as a potent multi-targeting anticancer agent, which makes it an appropriate candidate for drug delivery. Azurin may be delivered to cancer cells using different carriers like polymeric micro and nanoparticles. In the present study, azurin was extracted from the bacterial host and loaded into chitosan particles. Then its effect on MCF-7 cell line was investigated. Chitosan-azurin particles were made using the ion gelation method. Results showed that chitosan-azurin particles are about 200 nm, and the loading of the protein in particles did not affect its integrity. The MTT assay showed a significant reduction in cell viability in azurin and chitosan-azurin-treated cells. The toxicity level after 5 days was 63.78% and 82.53% for free azurin and chitosan-azurin-treated cells, respectively. It seems using an appropriate carrier system for anticancer proteins like azurin is a promising tool for developing low side effect anticancer agents.

We studied Zeta potentials of nanoparticles titanium dioxides （nTiO₂） in different concentration of NaNO₃ and phosphate (P) solutions. In addition, the effect of flow rate on the transport of nTiO₂ in P was investigated at pH＝6.5. Experimental results show that the Zeta potential of nTiO₂ is compressed with the increasing ion concentration (IC) of NaNO₃ at pH＝6.5. The negative charge increases with the augment of P. Therefore, the high P and low NaNO3 induce the stabilization of nTiO₂ aggregates. The transport experiments suggest that the rapid flow rate is favorable for the transportability of nTiO₂ and soluble phosphate. The breakthrough transport curves (BTCs) of nTiO₂ in sand columns can be fitted well with two-site kinetic attachment model. The modeling results suggest that the values of first-order attachment rate coefficients (k₂) and detachment rate coefficients (k_2d) on site 2 and first-order attachment rate coefficients (k₁) on site 1 are responsible to the attaching efficiency of nTiO₂ on sands and their transportability.

Burnout and workaholism, known to decrease efficiency and lead to depersonalisation, have negative effects on both employees and organisations. The survey aimed to analyse the correlation between burnout and workaholism among selected employees in the public and private sectors in Slovenia. The goal was to compare the results obtained in the administrative units and at the two selected banks. Various methodological approaches were employed, including statistical tests such as multivariate analysis, the Kolmogorov-Smirnov and Shapiro-Wilk tests, Spearman’s rank-order correlation coefficient, and the Mann-Whitney U test. Survey results indicate statistically significant differences between employees in administrative units and those in two banks. Workaholism is higher among employees in administrative units than at banks. Positive correlations were found between workaholism and the two dimensions of burnout, both among employees in administrative units and in the selected banks.

The article examines the issues of application and improvement of the methodology for evaluating industrial enterprises as recipients of state support within the framework of the implementation of industrial policy. The authors considered approaches to the content of industrial policy, investigated the factors influencing its efficiency, identified aspects of its imperfections that arise when applying an incomplete list of important parameters of economic development and ambiguity in the interpretation of previously applied estimates. The article presents proposals to improve the methodology for assessing potential recipients of state support based on the development of a comprehensive indicator for assessing enterprises (recipients of support), taking into account not only the classical parameters of the economic efficiency of industrial enterprises applying for state financial assistance, but also such aspects as the development of budgetary funds, belonging to priority sectors of the economy, characteristics of sustainable development and export and innovation potential. Combining the results of a comprehensive assessment of the recipient of state support with a map of the business demography of the territory allows making a decision not only about the fact of support and its efficiency, but also to predict the assessment of the life cycle of the enterprise and its subsequent development.