Accurate drug-drug interaction (DDI) prediction is essential to prevent adverse effects, especially with the increased use of multiple medications during the COVID-19 pandemic. Traditional machine learning methods often miss the complex relationships necessary for effective DDI prediction. This study introduces a deep learning-based classification framework to assess adverse effects from interactions between Fluvoxamine and Curcumin. Our model integrates a wide range of drug-related data (e.g., molecular structures, targets, side effects) and synthesizes them into high-level features through a specialized deep neural network (DNN). This approach significantly outperforms traditional classifiers in accuracy, precision, recall, and F1-score. Additionally, our framework enables real-time DDI monitoring, which is particularly valuable in COVID-19 patient care. The model’s success in accurately predicting adverse effects demonstrates the potential of deep learning to enhance drug safety and support personalized medicine, paving the way for safer, data-driven treatment strategies.

In the rapidly evolving landscape of China’s pharmaceutical industry, this study investigates how pharmaceutical enterprises can achieve profitable sales innovation amid the process of digital transformation. Grounded in the Affordance theory, it posits that the positive impact of digital transformation on sales innovation is driven by the affordance afforded by digital technology and ubiquity. The research focuses on A-share pharmaceutical companies in China, utilizing data from 2012 to 2022 and employing multiple regression analysis to examine the influence of digital transformation on corporate sales innovation. The results demonstrate a significant positive effect of digital transformation on sales innovation. The study further categorizes digital transformation into technological affordance and ubiquity affordance, separately validating their roles in promoting sales innovation. Moreover, by considering synergistic effects, the research unveils the intricate relationship between digital transformation and corporate innovation performance. The findings provide a fresh perspective on understanding how digital technology propels sales innovation and offer concrete guidance for the digital transformation practices in the pharmaceutical industry.

The study’s goal is to evaluate how microfinance initiatives affect women’s empowerment in Bangladesh. For this study, we analyzed data on a variety of women’s empowerment-related issues, including both beneficial and detrimental elements that stand in the way of women’s empowerment. Therefore, in order to accomplish the specified goal, we choose a suitable and intentional methodology. We employ diverse data gathering approaches to examine the gathered data and achieve the primary goal of the research project. It presents the positive effects of microfinance on women, such as (1) the enhancement of women’s authority in financial affairs; and (2) the augmentation of their ability to make decisions in household; and (3) community matters following their participation in the microfinance program. This also provides an analysis of the data pertaining to the adverse effects of microfinance on women. It examines how women encounter various challenges and engage in unethical behaviors after obtaining a loan, leading to heightened levels of stress following their participation in the microfinance program. This study looks into the advantages and disadvantages of Grameen Bank’s microcredit program for women. A questionnaire gathered primary data for this study from women participating in the microfinance program in Gopalgonj. To collect information and comprehend respondent behavior, I used case study, analytical and descriptive study design. Regression analysis, correlation, and percentage are used to examine the data. The findings indicate that women’s decision-making skills have improved due to their financial stability, but they have also experienced increased life challenges and high levels of stress.

The study documents the model of the knowledge transfer process between the University, the Vocational Training Center and the industrial actors. The research seeks to answer to the following questions. Where is new knowledge generated? Where does knowledge originate from? Is there a central actor? If so, which organization? Hypotheses tested by the research: H1: Knowledge starts from the higher education institution. H2: Most “new knowledge” is generated in universities and large multinational companies. H3: The university is a central actor in the knowledge flow, transmitting both hard and soft skills, as well as subject (‘know-what’), organizational (‘know-why’), use (‘know-how’), relational (‘know-who’), and creative (‘care-why’) knowledge. The aim of the research is to model the way of knowledge flow between the collaborating institutions. The novelty of this research is that it extends the analysis of the knowledge flow process not only to the actors of previous researches (higher education institutions, business organizations, and government) but also to secondary vocational education and training institutions. The methodology used in the research is the analysis of the documents of the actors investigated and the questionnaire survey among the participants. Knowledge transfer is the responsibility of the university and its partner training and business organizations. In vocational education and training, knowledge flows based on the knowledge economy, innovation and technological development are planned, managed and operational. The research has shown that knowledge is a specific good that it is indivisible in its production and consumption, that it is easy and cheap to transfer and learn.

Temperament education encompasses a wide range of concepts, focusing particularly on emotions within the context of Chinese culture. This article examines emotions through three key aspects: basic concepts, performance analysis, and intentional management. Understanding the basic concepts of emotions is essential. In Chinese culture, emotions are seen as complex experiences that influence individual behavior and social interactions. The seven emotions and six desires highlight the cultural significance of emotions in shaping human experience and communal harmony. Next, emotion performance analysis explores how emotions manifest in different situations. Traditional Chinese philosophy emphasizes the connection between emotions and moral decisions, underscoring the importance of emotional expression for balance and harmony. By analyzing normal stress responses and their variations, individuals can better understand their emotional patterns and triggers, affecting their relationships and decision-making. Lastly, intentional emotion management involves actively shaping emotional responses to achieve desired outcomes. Techniques like mindfulness and reflection can cultivate emotional awareness and control. This holistic approach enables individuals to navigate challenges more effectively, fostering resilience and well-being, ultimately leading to personal growth and enriched interpersonal relationships. By understanding, analyzing, and managing emotions, one can create a more harmonious and fulfilling life. The article establishes an inner clue of temperament education in the conclusion part to make it more vivid and comprehensive. The limitation of the article is much more theoretical than experimental. That’s the future extension of the research expected.

Transit-oriented development is a concept that focuses on developing areas in and around transit nodes to create added value. The concept concentrates on integrating mass public transport networks with non-motorized modes of transport, minimizing the usage of motorized vehicles, and fostering the growth of dense, mixed-use areas with medium to high spatial intensity. This research examines the effects of altering the business model to create Transit Oriented Development (TOD) in Jakarta, contrasting it with PT Moda Raya Transports (PT MRT). We collected data by conducting in-depth interviews with experts and distributing questionnaires to seven respondents who work at this We used the Business Model Canvas (BMC) to identify business models and the internal resources needed for the implementation process. process. Therefore, six elements in BMC were used to conduct changes, and based on the results, RBV analysis was pe PT MRT needs to enhance its internal power to a competitive advantage level in order to effectively manage changes. We need to conduct further research on how the business model can influence the creation of transit-oriented development areas.

The article undertakes an exploration into the rather unexpected progressiveness exhibited by courts across the globe in bestowing protection upon LGBTQ rights. A three-pronged study, which encompasses an examination of the theoretical rationales, empirical investigations, and doctrinal underpinnings of the augmentation of LGBTQ rights in diverse locales, is executed. It is hypothesized that a prima facie paradox emerges, whereby LGBTQ rights have been safeguarded and advanced in an extraordinary fashion, while concurrently, a discernible general trend of deviation from liberal constitutionalism, rights safeguarding mechanisms, and the rule of law is observable in other arenas. This article scrutinizes this contention and discovers that it is substantiated by case law from various regions. Critical theory and Butler’s theory of performativity potentially offer the most cogent explanations for this paradox. They have led to the social embrace of LGBTQ rights, while simultaneously, the enactment or amplification of these rights even in illiberal states furnishes an effortless ‘triumph’ for illiberal political actors, which can be employed as a countermeasure against assaults on their liberal and democratic reputations.