The fast-growing field of nanotheranostics is revolutionizing cancer treatment by allowing for precise diagnosis and targeted therapy at the cellular and molecular levels. These nanoscale platforms provide considerable benefits in oncology, including improved disease and therapy specificity, lower systemic toxicity, and real-time monitoring of therapeutic outcomes. However, nanoparticles' complicated interactions with biological systems, notably the immune system, present significant obstacles for clinical translation. While certain nanoparticles can elicit favorable anti-tumor immune responses, others cause immunotoxicity, including complement activation-related pseudoallergy (CARPA), cytokine storms, chronic inflammation, and organ damage. Traditional toxicity evaluation approaches are frequently time-consuming, expensive, and insufficient to capture these intricate nanoparticle-biological interactions. Artificial intelligence (AI) and machine learning (ML) have emerged as transformational solutions to these problems. This paper summarizes current achievements in nanotheranostics for cancer, delves into the causes of nanoparticle-induced immunotoxicity, and demonstrates how AI/ML may help anticipate and create safer nanoparticles. Integrating AI/ML with modern computational approaches allows for the detection of potentially dangerous nanoparticle qualities, guides the optimization of physicochemical features, and speeds up the development of immune-compatible nanotheranostics suited to individual patients. The combination of nanotechnology with AI/ML has the potential to completely realize the therapeutic promise of nanotheranostics while assuring patient safety in the age of precision medicine.

The project of returning farmland to forest is a new project of increasing farmers' income, ecological efficiency and

benefiting the country. The key to the success of returning farmland to forest project is to strictly control the key technologies such as regional planning, forest species selection, tree species selection, good seedling, structural configuration, meticulous soil preparation, serious planting, tending and management. According to the actual

situation of Yuanling County, suitable for the tree, choose the market prospects, fast-growing tree species afforestation,

reasonable adjustment of forest structure, ecological benefits and economic benefits simultaneously, take high-

quality high-yield and efficient forestry development. Returning farmland to forest project has played huge ecological benefits, economic and social benefits.

The rise of internet-based pharmacies has transformed the healthcare sector, giving patients access to medications, information, and direct interaction with pharmacists. While online pharmacies have become popular around the world, there are challenges hindering their widespread use in developing countries due to a limited understanding of the factors affecting their acceptance and usage. To bridge this knowledge gap, a study utilized a model combining the unified theory of acceptance and use of technology (UTAUT 2) with the technology acceptance model (TAM) to explore the drivers behind online pharmacy usage in Oman. Through this framework, twelve hypotheses were. A survey involving 378 individuals familiar with online pharmacies was conducted. Structural equation modeling (SEM) was applied to analyze the data and test these hypotheses. The results indicate that factors such as perceived expectancy effort expectancy and facilitating conditions hedonic motivation, habit perceived risk, technology trust, and technology awareness play roles in influencing the adoption of online pharmacies in Oman. The findings suggest that personal innovation plays a moderating role in the connection between perceived risk and behavioral intention, while it has a negative moderating influence on the relationship between technology trust and behavioral intention. Word of mouth was identified as a moderator in enhancing the correlation between behavioral intention and online pharmacy adoption. This research emphasizes the moderating relationship of personal innovation and word of mouth on shaping consumer attitudes towards online pharmacies and their acceptance. In summary, these results add to the existing knowledge on pharmacy adoption and in developed areas such as provide practical insights for online pharmacy providers to improve their offerings and attract a larger customer base.

Natural forests and abandoned agricultural lands are increasingly replaced by monospecific forest plantations that have poor capacity to support biodiversity and ecosystem services. Natural forests harbour plants belonging to different mycorrhiza types that differ in their microbiome and carbon and nutrient cycling properties. Here we describe the MycoPhylo field experiment that encompasses 116 woody plant species from three mycorrhiza types and 237 plots, with plant diversity and mycorrhiza type diversity ranging from one to four and one to three per plot, respectively. The MycoPhylo experiment enables us to test hypotheses about the plant species, species diversity, mycorrhiza type, and mycorrhiza type diversity effects and their phylogenetic context on soil microbial diversity and functioning and soil processes. Alongside with other experiments in the TreeDivNet consortium, MycoPhylo will contribute to our understanding of the tree diversity effects on soil biodiversity and ecosystem functioning across biomes, especially from the mycorrhiza type and phylogenetic conservatism perspectives.

Soil and groundwater remediation Act was enacted in year 2000. More than ten years has already passed,  Monitoring project has been completed,pollution status has been defined,contaminated sites depollution have been launched,a great progress has been made. This paper majorly to depict the extensive farmland soil qauality monittoring which is unpredent in Taiwan and believe has never been done worldwide.

This project was initiated from February 8^th, 2002 to August 8^th, 2002. The project tasks including digitalization of cadastre, farmland listing, basic information collecting, field investigation, sampling & analysis planning, field sampling, soil sample analysis, data evaluation, suggestion of contaminated farmland control, and analysis of potential pollution sources and transfer routes.

2,251 soil samples,had been sampled from Chang-Hwa County, Yun-Lin County, Nan-Tao County, and Chia-Yi City, and been analyzed in this project. 44% of these samples concentration exceed the soil pollution control standard (Table 1), including 492 farmlands (125.65 ha registered) with total contaminated farming area of 108.38 ha in Chang-Hwa, and 6 farmlands (0.39 ha registered) with total contaminated farming area of 0.39 ha in Nan-Tao County. However, the concentration of samples from Ynu-Lin County and Chia-Yi City do not exceed the soil pollution control standard.

To coordinate with the investigation results of the relative project regarding to water and sediment quality of irrigation channels in Chang-Hwa area, the pollution sources are preliminary concluded to be the irrigation channels surrounding the farmlands in Chang-Hwa area. As to the Nan-Tao County, the abandoned brick furnace plants neighboring the farmland are suspected to be the pollution sources.

The results show that the soil of the investigation area in Chang-Hwa County is the most polluted. Base on the Geostatistics study and the distribution of the irrigation channels; the area neighboring the investigated farmland in this project is suspected being polluted. For the farmlands exceeding soil control standard, Geostatistics method is suggested to coordinate with the information of the irrigation system to clarify the contaminated area so as to be the basis of land control and remediation work. As to the farmlands, not being investigated in this project but with high pollution potential according to the Geostatistics study, detail investigations are suggested. Regarding to soil pollution remediation, it is suggested to coordinate with the effluent control and irrigation channel remediation to achieve an all-out success.