Atomic interaction between mediator protein of human prostate cancer (PHPC) and Fe/C720 Buckyballs-Statin is important for medical science. For the first time, we use molecular dynamics (MD) approach based on Newton’s formalism to describe the destruction of PHPC via Fe/C720 Buckyballs-Statin with atomic accuracy. In this work, the atomic interaction of PHPC and Fe/C720 Buckyballs-Statin introduced via equilibrium molecular dynamics approach. In this method, each PHPC and Fe/C720 Buckyballs-Statin is defined by C, H, Cl, N, O, P, S, and Fe elements and contrived by universal force field (UFF) and DREIDING force-field to introduce their time evolution. The results of our studies regarding the dynamical behavior of these atom-base compounds have been reported by calculating the Potential energy, center of mass (COM) position, diffusion ratio and volume of defined systems. The estimated values for these quantities show the attraction force between Buckyball-based structure and protein sample, which COM distance of these samples changes from 10.27 Å to 2.96 Å after 10 ns. Physically, these interactions causing the destruction of the PHPC. Numerically, the volume of this biostructure enlarged from 665,276 Å3 to 737,143 Å3 by MD time passing. This finding reported for the first time which can be considered by the pharmaceutical industry. Simulations indicated the volume of the PHPC increases by Fe/C720 Buckyballs-Statin diffusion into this compound. By enlarging this quantity (diffusion coefficient), the atomic stability of PHPC decreases and protein destruction procedure fulfilled.

This research examines data from 1989 to 2022 across 48 Sub-Saharan African (SSA) countries using a novel panel data regression approach to uncover how conflict undermines economic stability. The study identifies the destruction of infrastructure, disruption of human capital development, and deterrence of investment as primary channels through which conflict negatively impacts economies. These findings support the hypothesis that armed conflict severely hampers economic performance in SSA, highlighting the urgency for effective conflict resolution strategies and robust institutional frameworks. The negative impacts extend beyond immediate losses, altering income growth trajectories and perpetuating poverty long after hostilities cease. Regional spillover effects emphasize the interconnectedness of SSA economies, where conflict in one country affects its neighbors. The research provides innovative insights by disaggregating impact pathways and employing a robust methodology, revealing the complexity of conflict's economic consequences. It underscores the need for comprehensive policy interventions to foster resilience and sustainable development in conflict-prone regions. While there is evidence of potential post-conflict growth, the overall net effect of armed conflict remains profoundly negative, diminishing economic prospects. Future research should focus on strengthening long-term resilience mechanisms and policy measures to enhance the peace dividend. Addressing the root causes of conflict and investing in peace-building efforts are essential for transforming SSA's economic landscape and ensuring sustainable growth and development.

Small and medium-sized enterprises (SMEs) play a critical role in achieving environmental sustainability, particularly in developing economies where regulatory enforcement and resource constraints remain significant challenges. Drawing on Institutional Theory, this study examines how green leadership influences environmental performance in Ghanaian SMEs, with digital innovation as a mediating variable and environmental culture as a moderating variable. Institutional Theory provides the conceptual foundation for explaining how normative pressures embedded in leadership values and organizational culture, alongside mimetic pressures associated with digital innovation adoption, shape firms’ environmental outcomes. Using survey data collected from SMEs in Ghana and analyzed using Partial Least Squares Structural Equation Modeling (PLS-SEM), the results revealed that green leadership has a significant positive effect on both digital innovation and environmental performance. Digital innovation also significantly enhances environmental performance and partially mediates the relationship between green leadership and environmental performance. Notably, the findings demonstrated that environmental culture significantly moderates the relationship between digital innovation and environmental performance, with the effect stronger in organizations with a well-developed environmental culture. This indicates that internalized environmental values amplify the effectiveness of digital innovation initiatives. The study contributes to the sustainability and organizational literature by extending Institutional Theory to the SME context in a developing economy and by clarifying the conditional role of environmental culture in translating digital innovation into superior environmental performance. Practically, the findings suggest that SME leaders and policymakers should promote environmentally oriented leadership, invest in digital innovation, and cultivate strong environmental cultures to enhance sustainability outcomes.

Ukrainian Human Resource (HR) practices have multiple difficulties from economic changes combined with digital transformation and workforce instability brought on by the war in 2022. The study examines Ukrainian HR practices between 2015 and 2024, focusing on the digitalization of HR systems, talent development, staff engagement, and hiring strategies. It considers the effects of organizational size and industry type. The study combined interviews with 30 HR professionals and surveyed 150 organizations from different industry groups and sizes. Our data required both quantitative statistical tests and manual content breakdown with codes. Research has shown significant differences between Information Technology (IT) and farming firms, as 89% of IT businesses have integrated artificial intelligence (AI)-powered HR tools. In comparison, only 15% of agricultural companies have adopted them. Small and medium-sized enterprises (SMEs) showed less commitment to digital transformation and European Union (EU) requirements than large enterprises, which adopted these systems at rates of 75% and 88%, respectively. Western Ukraine first established mental health initiatives during the crisis, and Eastern Ukraine moved toward decentralized administration. Digitalization assistance for small businesses, along with EU and local human resources frameworks, should form the basis of our suggestions. This research calls for flexible people management methods to boost the Ukrainian workspace’s ability to recover from shocks.

Objective: This study synthesizes current evidence on the role of Artificial Intelligence (AI) and, where relevant, Open Science (OS) practices in enhancing Human Resource Management (HRM) performance. It focuses on recruitment processes, ethical considerations, and employee participation. Methodology: A systematic literature review was conducted in Scopus covering the period 2019–2024, following PRISMA guidelines. The initial search yielded 1486 records. After de-duplication and screening using Rayyan, 66 studies (≈ 4.4%) met the inclusion criteria, which targeted peer-reviewed works addressing AI-supported HR decision-making. A combined content and bibliometric analysis was performed in R (Bibliometrix) to identify thematic patterns and conceptual structures. Results: Analysis revealed four thematic clusters: 1) Implementation and employee participation emphasizing human-in-the-loop approaches and effective change management; 2) ethical challenges including algorithmic bias, transparency gaps, and data privacy risks; 3) data-driven decision-making delivering higher accuracy, fewer errors, and personalized recruitment and performance assessment; 4) operational efficiency enabling faster workflows and reduced administrative workloads. AI tools consistently improved selection quality, while OS practices promoted transparency and knowledge sharing. Implications: The successful adoption of AI in HRM requires employee engagement, strong ethical safeguards, and transparent data governance. Future research should address the long-term cultural, organizational, and well-being impacts of AI integration, as well as its sustainability.

The artificial intelligence (AI)-based architect’s profile’s selection (simply iSelection) uses a polymathic mathematical model and AI-subdomains’ integration for enabling automated and optimized human resources (HR) processes and activities. HR-related processes and activities in the selection, support, problem-solving, and just-in-time evaluation of a transformation manager’s or key team members’ polymathic profile (TPProfile). Where a TPProfile can be a classical business manager, transformation manager, project manager, or an enterprise architect. iSelection-related selection processes use many types of artifacts, like critical success factors (CSF), AI-subdomain’ integration environments, and an enterprise-wide decision-making system (DMS). iSelection focuses on TPProfiles for various kinds of transformation projects, like the case of the transformation of enterprises’ HRs (EHR) processes, activities, and related fields, like enterprise resources planning (ERP) environments, financial systems, human factors (HF) evolution, and AI-subdomains. The iSelection tries to offer a well-defined (or specific) TPProfile, which includes HF’s original-authentic capabilities, education, affinities, and possible polymathical characteristics. Such a profile can also be influenced by educational or training curriculum (ETC), which also takes into account transformation projects’ acquired experiences. Knowing that selected TPProfiles are supported by an internal (or external) transformation framework (TF), which can support standard transformation activities, and solving various types of iSelection’s problems. Enterprise transformation projects (simply projects) face extremely high failure rates (XHFR) of about 95%, which makes EHR selection processes very complex.