Introduction: the presence of anti-CCP is an important prognostic tool for rheumatoid arthritis (RA), but its relationship with the activity of the disease and functional capacity is still being investigated. Objectives: to study the relationship between anti-CCP and the indices of disease activity, functional capacity and structural damage, by means of conventional radiography (CR) and magnetic resonance imaging (MRI), in stabilized RA. Methods: cross-sectional study of RA patients with one to 10 years of disease. The participants were subjected to clinical evaluation with anti-CCP screening. Disease activity was assessed by means of the Clinical Disease Activity Index (CDAI) and functional capacity by means of the Health Assessment Questionnaire (HAQ). CR was analyzed by the Sharp van der Heijde index (SmvH) and MRI by the Rheumatoid Arthritis Magnetic Resonance Image Scoring System (RAMRIS). Results: 56 patients were evaluated, with median (IIq) of 55 (47.5–60.0) years, 50 (89.3%) were female among whom 37 (66.1%) were positive for anti-CCP. The median (IIq) of CDAI, HAQ, SmvH and RAMRIS were 14.75 (5.42–24.97), 1.06 (0.28–1.75), 2 (0–8) and 15 (7–35), respectively. There was no association between anti-CCP and CDAI, HAQ, SmvH and RAMRIS. Conclusion: our results did not establish the association of anti-CCP with the severity of the disease. So far, we cannot corroborate the anti-CCP as a prognostic tool in RA established.
Imaging technology plays a key role in guiding endovascular treatment of aortic aneurysm, especially in the complex thoracoabdominal aorta. The combination of high quality images with a sterile and functional environment in the surgical suite can reduce contrast and radiation exposure for both patient and operator, in addition to better outcomes. This presentation aims to describe the current use of this technique, combining angiotomography and intraoperative cone beam computed tomography, image “fusion” and intravascular ultrasound, to guide procedures and thus improve the intraoperative success rate and reduce the need for reoperation. On the other hand, a procedure is described to create customized 3D templates with the high-definition images of the patient’s arterial anatomy, which serve as specific guides for making fenestrated stents in the operating room. These customized fenestration templates could expand the number of patients with complex aneurysms treated minimally invasively.
Ecuador acknowledges the need to improve infrastructure and resources for educational inclusion, but it faces challenges in effective implementation compared to developed countries that have made advancements in this area. The objective of this research was to map the regulations and practices related to the implementation of inclusive infrastructure and educational resources at the international level, identifying knowledge gaps and opportunities for adaptation in Ecuador. An exploratory theoretical review was conducted following PRISMA-ScR guidelines, using searches in academic databases and official documents. Qualitative and regulatory studies from the United States, Finland, Canada, and Japan were selected, analyzing 16 scientific articles and 11 official documents. The results reveal that Ecuador faces challenges in the implementation of inclusive regulations, particularly in infrastructure and resources, highlighting the need to establish national accessibility standards, invest in assistive technologies, and offer continuous teacher training to enhance educational inclusion. The research uncovered a negative cycle where the lack of effective implementation of inclusive regulations perpetuates inequality and reinforces institutional inertia. For successful reform, the regulatory structure, resource management, and educational culture in Ecuador must be addressed simultaneously.
The objectives achieved in the Paris Agreement to reduce greenhouse gas emissions and reduce dependence on fossil fuels have caused, in recent years, a growing importance on sustainability in companies in order to reduce Environmental, social and economic impacts. This study is focused on understanding how the variation in West Texas Intermediate crude oil prices affects the Dow Jones Sustainability Index, and therefore the companies included in it, and vice versa. The research aims to examine the statistical properties of both indices, using fractional integration methods, the fractional cointegration vector autoregressive (FCVAR) approach and the continuous wavelet transform (CWT) technique. The results warn of a change in trend, with the application of extraordinary measures being necessary to return to the original trend, while the analysis of cointegration and wavelet analysis measures reflect that an increase in those adopted based on sustainability by the different companies that make up the index imply a drop in the price of crude oil.
This study aims to determine the effects of monosodium glutamate (MSG) dosage on the yield of long beans (Vigna sinensis L.) of the Peleton variety. The use of MSG as a food ingredient has been a topic of debate, but research on its impact on plant growth is still limited, especially regarding long beans. Therefore, this research is important for providing further understanding of the influence of MSG on long beans plants. The study was conducted from July to October 2023 in Mata Air Village, Central Kupang District, Kupang Regency, East Nusa Tenggara Province. The research method used was a Randomized Complete Block Design (RCBD) with 9 treatments and 3 replications. The treatments included: No MSG, MSG at doses of 2.5 g/plant, 5 g/plant, 7.5 g/plant, 10 g/plant, 12.5 g/plant, 15 g/plant, 17.5 g/plant, and 20 g/plant. Parameters observed included flowering age (days), number of pods (pieces), pod length (cm), and pod weight (g). Based on the results and discussion, it can be concluded that MSG application had a significant effect on the number, length, and weight of pods, but had a non-significant effect on flowering age. The treatment of 15 g/plant was identified as the optimal MSG dosage for the plants, resulting in the highest number of pods (16.2), longest pod length (60.4 cm), and highest pod weight (256.4 g/plant). This research is innovative in exploring the potential use of monosodium glutamate (MSG) on long beans plants, particularly the Peleton variety. The focus on MSG application as a growth stimulant is an innovative step that has been less studied previously. The discovery of the optimal MSG dosage (15 g/plant) for achieving the best results provides valuable information for farmers to enhance productivity efficiently, sustainably, and environmentally friendly. Information about MSG’s potential as a plant stimulant can serve as a starting point for more sustainable agricultural strategies aimed at optimizing available resources.
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