Objective: To investigate the value of differential diagnosis of hepatocellular carcinoma (HCC) and cirrhotic nodules via radiomics models based on magnetic resonance images. Background: This study is to distinguish hepatocellular carcinoma and cirrhotic nodules using MR-radiomics features extracted from four different phases of MRI images, concluded T1WI, T2WI, T2 SPIR and delay phase of contrast MRI. Methods: In this study, the four kind of magnetic resonance images of 23 patients with hepatocellular carcinoma (HCC) were collected. Among them, 12 patients with liver cirrhosis were used to obtain cirrhotic nodules (CN). The dataset was used to extract MR-radiomics features from regions of interest (ROI). The statistical methods of MRradiomics features could distinguish HCC and CN. And the ability of radiomics features between HCC and CN was estimated by receiver operating characteristic curve (ROC). Results: A total of 424 radiomics features were extracted from four kind of magnetic resonance images. 86 features in delay phase of contrast MRI,86 features in spir phase of T2WI,86 features in T1WI and 88 features in T2WI showed statistical difference (p < 0.05). Among them, the area under the curves (AUC) of these features larger than 0.85 were 58 features in delay phase of contrast MRI, 54 features in spir phase of T2WI, 62 features in T1WI and 57 features in T2WI. Conclusions: Radiomics features extracted from MRI images have the potential to distinguish HCC and CN.
Eco-friendly and greener barrier materials are required to replace the synthetic packaging materials as they produce a threat to environment. These can be fabricated by natural polymers such as cellulose nanofiber (CNF). The sustainability of CNF was so amazing due to its potential for circular economy and provides alternative platform for synthetic plastics. The challenging task to fabricate CNF films still existed and also current methods have various limitations. CNF films have good oxygen permeability and the value was lower than synthetic plastics. However, CNF films have poor water vapour permeability and higher than that of synthetic plastics. The fabrication method is one of strong parameters to impact on the water permeability of CNF films. The deposition of CNF suspension on the stainless-steel plate via spraying, is a potential process for fabrication for CNF films acting as barrier material against water vapour. In spraying process, the time required to form CNF films in diameter of 15.9 cm was less than 1 min and it is independent of CNF content in the suspension. The uniqueness of CNF films via the spraying process was their surfaces, such as rough surface exposed to air and smooth surface exposed to stainless steel. Their surfaces were investigated by SEM, AFM and optical profilometry micrographs, confirming that the smooth surface was evaluated notable lower surface roughness. The spray coated surface was smooth and glossy and its impact on the water vapor permeability remains obscure. The spraying process is a flexible process to tailor the basis weight and thickness of CNF films can be adjusted by the spraying of CNF suspension with varying fibre content. The water vapour permeability of CNF films can be tailored via varying density of CNF films. The plot between water vapour transfer rate (WVTR)/water vapour and density of CNF films has been investigated. The WVP of spray coated CNF films varied from 6.99 ± 1.17 × 10−11 to 4.19 ± 1.45 × 10−11 g/m.s.Pa. with the density from 664 Kg/m3 to 1,412.08 Kg/m3. The WVP of CNF films achieved with 2 wt% CNF films (1,120 Kg/m3) was 3.91 × 10−11 g/m.s.Pa. These values were comparable with the WVP of synthetic plastics. Given this correspondence, CNF films via spraying have a good barrier against water vapour. This process is a potential for scale up and commercialization of CNF films as barrier materials.
This paper highlights the complex relationship between entrepreneurship, sustainable development, and economic growth in 41 European countries, using a reliable K-Means cluster analysis. The research thoroughly evaluates three key factors: the SDG Index for sustainable development, GDP per capita for economic well-being, and the New Business Density Rate for entrepreneurial activity. Our methodology reveals three distinct narratives that embody varying degrees of economic vitality and sustainability. Cluster 1 comprises the financially stable and sustainability-oriented countries of Western and Northern Europe. Cluster 2 showcases the variegated economic and sustainability initiatives in Central and Southern Europe. Cluster 3 envelopes the economic titans with noteworthy business expansion but with the potential for better sustainable practices. The analysis reveals a favourable association between economic prosperity and sustainable development within clusters, although with nonlinear intricacies. The research concludes with a series of strategic imperatives specifically crafted for each cluster, promoting economic variation, increased sustainability, invention, and worldwide collaboration. The resulting findings highlight the crucial need for policy-making that considers the specific context and the potential for combined European resilience and sustainability.
This paper conducts a comparative analysis of mentoring and metacognition in education, unveiling their intricate connections. Both concepts, though seemingly disparate, prove to be interdependent within the educational landscape. The analysis showcases the dynamic interplay between mentoring and metacognition, emphasizing their reciprocal influence. Metacognition, often perceived as self-awareness and introspection, is found to complement the relational and supportive nature of mentoring. Within this context, metacognitive education within mentoring emerges as a vital component. Practical recommendations are offered for effective metacognitive training, highlighting its role in enhancing cognitive and metacognitive skills. Moreover, the paper introduces the concept of a “mentoring scaffolding system.” This system emphasizes mentor-led gradual independence for mentees, facilitating their professional and personal growth. The necessity of fostering a metacognition culture in education is a central theme. Such a culture promotes improved performance and lifelong learning. The paper suggests integrating metacognition into curricula and empowering learners as essential steps toward achieving this culture. In conclusion, this paper advocates for the integration of metacognition into mentoring and education, fostering self-awareness, independence, and adaptability. These attributes are deemed crucial for individuals navigating the challenges of the information age.
This research explores the necessity and the effect of job resources for undergraduates’ career satisfaction during work experience in an apprenticeship program. Additionally, we examine the extent to which a supportive environment enhances apprentice career satisfaction by providing access to valuable learning experiences. We propose PLS equation modelling with a sample of 81 students who completed a dual apprenticeship degree in Business Administration and Management at Spanish University. The study finds that all three workplace job resources are necessary for career satisfaction among apprentices. Learning opportunities and social relations have significant effects, while job control contributes only marginally. It highlights that learning opportunities enhance social relations, emphasizing the importance of feedback. The study extends job resource research to university level apprenticeships, showing that without these resources, apprentices lack career satisfaction. It highlights that learning opportunities are crucial for satisfaction through social relations and offers guidance for designing effective workplace training programs.
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