The challenge of rural electrification has become more challenging today than ever before. Grid-connected and off-grid microgrid systems are playing a very important role in this problem. Examining each component’s ideal size, facility system reactions, and other microgrid analyses, this paper proposes the design and implementation of an off-grid hybrid microgrid in Chittagong and Faridpur with various load dispatch strategies. The hybrid microgrids with a load of 23.31 kW and the following five dispatch algorithms have been optimized: (i) load following, (ii) HOMER predictive, (iii) combined dispatch, (iv) generator order, and (v) cycle charging dispatch approach. The proposed microgrids have been optimized to reduce the net present cost, CO₂ emissions, and levelized cost of energy. All five dispatch strategies for the two microgrids have been analyzed in HOMER Pro. Power system reactions and feasibility analyses of microgrids have been performed using ETAP simulation software. For both the considered locations, the results propound that load-following is the outperforming approach, which has the lowest energy cost of $0.1728/kWh, operational cost of $2944.13, present cost of $127,528.10, and CO₂ emission of 2746 kg/year for the Chittagong microgrid and the lowest energy cost of $0.2030/kWh, operating cost of $3530.34, present cost of 149,287.30, and CO₂ emission of 3256 kg/year for the Faridpur microgrid with a steady reaction of the power system.

The present paper discusses the case of the Madrid Nuevo Norte Project (MNNP) in order to examine the relation of this mega-project with the city’s sustainable development. For this reason, the study used a qualitative approach using semi-structural interviews with experts (Madrid’s town hall, Madrid State, and the program management office and other external) that relayed strongly with MNNP. The expert panel requirements are split in six expertise areas: sustainability, urban development, urban planning, government or public affairs, project management or Madrid Nuevo Norte (MNN) key stakeholders. The study highlighted the vital importance of MNNP as a flagship sustainable project for the rest of Europe, that meets sustainability criteria for contributing substantially in the improvement of the quality of life of final users and for the community in general. For instance, it contributes to the regeneration of the city’s degraded area, to the interconnection of an isolated part of the city and public transportation connection, improving the external image of Madrid. Despite of it, there are some challenges that should be carefully managed such as applying sustainable solutions from other cities not properly tailored to Madrid, housing pricing accessibility increase due to the lack of terrain in Madrid and the politization of the project as discussion topic between local parties. In this context, local authorities should give particular emphasis in complying with the principles of sustainability for improving the overall performance of MNNP, ensuring social justice and prosperity for the people of Madrid.

In the last several decades, cardiovascular diseases (CVDs) have emerged as a major hazard to human life and health. Conventional formulations for the treatment of CVD are available, but they are far from ideal because of poor water solubility, limited biological activity, non-targeting, and drug resistance. With the advancement of nanotechnology, a novel drug delivery approach for the treatment of CVDs has emerged: nano-drug delivery systems (NDDSs). NDDSs have shown significant advantages in tackling the difficulties listed above. Cytotoxicity is a difficulty with the use of non-destructive DNA sequences. NDDS categories and targeted tactics were outlined, as well as current research advancements in the diagnosis and treatment of CVDs. It’s possible that gene therapy might be included into nano-carriers in the delivery of cardiovascular medications in the future. In addition, the evaluation addressed the drug’s safety.