Artificial intelligence chatbots can be used to conduct research effectively and efficiently in the fifth industrial revolution. Artificial intelligence chatbots are software applications that utilize artificial intelligence technologies to assist researchers in various aspects of the research process. These chatbots are specifically designed to understand researchers’ inquiries, provide relevant information, and perform tasks related to data collection, analysis, literature review, collaboration, and more. The purpose of this study is to investigate the use of artificial intelligence chatbots for conducting research in the fifth industrial revolution. This qualitative study adopts content analysis as its research methodology, which is grounded in literature review incorporating insights from the researchers’ experiences with utilizing artificial intelligence. The findings reveal that researchers can use artificial intelligence chatbots to produce quality research. Researchers are exposed to various types of artificial intelligence chatbots that can be used to conduct research. Examples are information chatbots, question and answer chatbots, survey chatbots, conversational agents, peer review chatbots, personalised learning chatbots and language translation chatbots. Artificial intelligence chatbots can be used to perform functions such as literature review, data collection, writing assistance and peer review assistance. However, artificial intelligence chatbots can be biased, lack data privacy and security, limited in creativity and critical thinking. Researchers must be transparent and take in consideration issues of informed content and data privacy and security when using artificial intelligence chatbots. The study recommends a framework on artificial intelligence chatbots researchers can use to conduct research in the fifth industrial revolution.

Protein- and peptide-based medications are recognized for their effectiveness and lower toxicity compared to chemical-based drugs, making them promising therapeutic agents. However, their application has been limited by numerous delivery challenges. Polymeric nanostructures have emerged as effective tools for protein delivery due to their versatility and customizability. Polymers’ inherent adaptability makes them ideal for meeting the specific demands of protein-delivery systems. Various strategies have been employed, such as enzyme inhibitors, absorption enhancers, mucoadhesive polymers, and chemical modifications of proteins or peptides. This study explores the hurdles associated with protein and peptide transport, the use of polymeric nanocarriers (both natural and synthetic) to overcome these challenges, and the techniques for fabricating and characterizing nanoparticles.

Gout is an arthritis characterized by the deposition of sodium monoacid crystals in the synovial membrane, articular cartilage, and periarticular tissues that leads to an inflamatory process. In most cases, the diagnosis is established by clinical criteria and analysis of the synovial fluid for MSU crystals. However, gout may manifest in atypical ways and make diagnosis difficult. In these situations, imaging studies play a fundamental role in helping to confirm the diagnosis or even exclude other differential diagnoses. Conventional radiography is still the most commonly used method in the follow-up of these patients, but it is a very insensitive test, because it only detects late changes. In recent years, advances in imaging methods have emerged in relation to gout. Ultrasound has proven to be a highly accurate test in the diagnosis of gout, identifying MSU deposits in articular cartilage and periarticular tissues, and detecting and characterizing tophi, tendinopathies, and tophi enthesopathies. Computed tomography is an excellent exam for the detection of bone erosions and evaluation of spinal involvement. Dual-energy computed tomography, a new method that provides information on the chemical composition of tissues, allows identification of MSU deposits with high accuracy. MRI can be useful in the evaluation of deep tissues not accessible by ultrasound. In addition to diagnosis, with the emergence of drugs that aim to reduce the tophaceous burden, imaging examinations become a useful tool in the follow-up treatment of gout patients.

While infrastructure provides necessary public services and is vital for the socio-economic development of a nation, public funds alone cannot finance all infrastructure needs in society, especially after the COVID-19 pandemic, where many countries are facing budget deficits. Although private financing schemes, such as public-private partnerships (PPPs) and land value capture, have been considered intensively, they have yet to produce adequate private capital flows to infrastructure projects due to a lack of incentives for private investors. Against the background, this paper proposes a new financing mechanism in which governments might divert some of the increased tax revenue from the spillover effects of newly constructed infrastructures to fund the private sector through grants or subsidies. The empirical work in Vietnam shows a significant increase in tax revenues after completing two expressways, supporting our idea about spillover effects, which includes small- and medium-sized enterprise (SME) development. This study’s results suggest that spillover effects can bring new opportunities for governments and multilateral development banks (MDBs) to implement infrastructure projects with greater private sector involvement in the region. It also proposes some financial schemes, such as land capture and financing for business startups, including SMEs, to enhance the spillover effects of infrastructure.

This article examines the female figures in Eileen Chang’s works, exploring their female consciousness in different social environments and historical backgrounds, as well as the influence of Eileen Chang’s legendary experiences on their formation. This article delves into the female consciousness depicted in Eileen Chang’s works, revealing her contributions to modern Chinese literature and social culture. The female consciousness in Eileen Chang’s works reflects her concern for the status of women and serves as a critique of patriarchal society and feudal culture. The female characters portrayed by Eileen Chang exhibit strong individuality and self-awareness, yet they still struggle to break free from the constraints of patriarchal society and feudal culture, losing themselves in the “foreign enclave society”. Eileen Chang’s legendary life greatly impacted the development of her female consciousness.