The present work shows an application of the Chan-Vese algorithm for the semi-automatic segmentation of anatomical structures of interest (lungs and lung tumor) in 4DCT images of the thorax, as well as their three-dimensional reconstruction. The segmentation and reconstruction were performed on 10 CT images, which make up an inspiration-expiration cycle. The maximum displacement was calculated for the case of the lung tumor using the reconstructions of the onset of inspiration, the onset of expiration, and the voxel information. The proposed method achieves appropriate segmentation of the studied structures regardless of their size and shape. The three-dimensional reconstruction allows us to visualize the dynamics of the structures of interest throughout the respiratory cycle. In the future, it is expected to have more evidence of the good performance of the proposed method and to have the feedback of the clinical expert, since the knowledge of the characteristics of anatomical structures, such as their dimension and spatial position, helps in the planning of Radiotherapy (RT) treatments, optimizing the radiation dose to cancer cells and minimizing it in healthy organs. Therefore, the information found in this work may be of interest for the planning of RT treatments.

Adsorption is a widely used method for the treatment of dissolved contaminants. Various agro-industrial wastes have been explored as potential adsorbents, showing high efficiency in dye removal. Each adsorbate-adsorbent pair needs kinetic, and equilibrium models to scale up this process. In this work, the equilibrium, kinetics and thermodynamics of the corn Tuza-Red 40 system were evaluated under batch system at ph = 2.0 at temperatures of 25, 40, and 55 °C. The Langmuir, Freundlich and Temkin models were selected for the isotherm representation, while the Lagergren, Ho, and Elovich equations for the kinetics of the process. The Freundlich model presented the best fit to the isotherms, the adsorption kinetics was best described by the Ho equation, and the values for Gibbs free energy and entropy indicated the spontaneity and feasibility of the process.

Potassium dihydrogen phosphate, KH2PO4 (KDP) crystal is an excellent electro-optical nonlinear optical crystal with large electro-optical nonlinear coefficient, high laser damage threshold, and laser frequency doubling effect, electro-optical effect , Piezoelectric effects and other special features, widely used in inertial confinement fusion engineering (ICF) and electro-optical switching devices. Therefore, its growth mechanism, growth process and performance have been systematically studied. In the process of KDP crystal growth, it is found that the stability of the growth solution is an important factor affecting the quality of crystal growth. Therefore, in recent years, more and more research on the stability of the solution, such as the study of ph, doping, supersaturation, overheating time on the stability of the solution. Among them, the research on the doping is mostly reported, and the research on this aspect is mainly focused on two aspects. On the one hand, it is the study of the stability of the solution under doping, and the other is the effect of doping on the optical quality of the crystal. In fact, the stability of the growth solution and the quality of crystal growth is directly related to the quality, but the existing research to isolate the two researches. Therefore, the experiment will be carried out in the case of double-doped KDP solution stability, KDP crystal growth and crystal optical quality and other experiments, and in-depth analysis of the impact of solution stability and crystal optical quality of the reasons, while the solution stability and The relationship between the optical quality of the crystal is briefly analyzed.

This article explores the implications of directive change management, characterized by top-down leadership and minimal employee involvement, on organizational dynamics, employee morale, and job security. This approach's psychological and operational impacts are underscored, emphasizing the imperative of addressing employee perceptions and fostering trust. Strategies for rebuilding trust and enhancing morale post-directive change management are presented, including transparent communication, participative decision-making, and recognition of employee contributions. The significance of enhancing job security through clear policies, open dialogue, and robust mental health and well-being support systems is highlighted. Practices that encourage job dedication are introduced, emphasizing goal alignment, meaningful work design, and a culture of innovation and continuous improvement. Long-term strategies for cultivating a healthy workplace, such as establishing feedback mechanisms, investing in leadership development, and maintaining organizational adaptability, are also discussed. This brief article is an introductory resource for business leaders, managers, and change practitioners seeking to be better equipped with the necessary tools and strategies to navigate the post-implementation effects of directive change management. It is anticipated that this information can assist leaders and organizations in navigating the challenges of directive change management, promoting resilience, employee well-being, and sustainable organizational success.

The research issue at hand pertains to the intricate mechanisms of state regulation that govern the economy of Kazakhstan, particularly in the context of the international sanctions that have been instituted by the nations comprising the Eurasian Economic Union. In order to thoroughly investigate this complex subject matter, this scholarly paper employs a variety of sophisticated methodologies grounded in bibliometric analyses of the most recent 90 academic papers that focus on the various mechanisms of state regulation pertinent to the economic landscape of Kazakhstan. As a subsequent phase in this research endeavor, the modeling of higher-order moments is undertaken with the express aim of delineating the multifaceted ramifications that stem from a singular and isolated perturbation affecting one of the key variables encapsulated within the higher-order moments model. This detailed analytical approach facilitates an in-depth exploration of both the immediate outcomes and the subsequent values of the endogenous variables that are under scrutiny. The innovative aspect of this article’s findings lies in the comprehensive analysis dedicated to the state regulation of Kazakhstan’s economy, which is significantly influenced by the international sanctions that have been imposed by member countries of the Eurasian Economic Union. The outcomes of this research provide a methodical and scientifically rigorous framework for understanding the overarching system of state regulation, which is of paramount importance for cultivating sustainable development within the socio-economic dynamics that characterize the nation of Kazakhstan.