Multiple myeloma (MM) is a hematologic cancer characterized by clonal proliferation of plasma cells within the bone marrow. It is the most serious form of plasma cell dyscrasias, whose complications—hypercalcemia, renal failure, anemia, and lytic bone lesions—are severe and justify the therapeutic management. Imaging of bone lesions is a cardinal element in the diagnosis, staging, study of response to therapy, and prognostic evaluation of patients with MM. Historically, the skeletal radiographic workup (SRW), covering the entire axial skeleton, has been used to detect bone lesions. Over time, new imaging techniques that are more powerful than SRW have been evaluated. Low-dose and whole-body computed tomography (CT) supplants SRW for the detection of bone involvement, but is of limited value in assessing therapeutic response. Bone marrow MRI, initially studying the axial pelvic-spinal skeleton and more recently the whole body, is an attractive alternative. Beyond its non-irradiating character, its sensitivity for the detection of marrow damage, its capacity to evaluate the therapeutic response and its prognostic value has been demonstrated. This well-established technique has been incorporated into disease staging systems by many health systems and scientific authorities. Along with positron emission tomography (PET)-18 fluorodeoxyglucose CT, it constitutes the current imaging of choice for MM. This article illustrates the progress of the MRI technique over the past three decades and situates its role in the management of patients with MM.

This research study explores the addition of chromium (Cr⁶⁺) ions as a nucleating agent in the alumino-silicate-glass (ASG) system (i.e., Al₂O₃-SiO₂-MgO-B₂O₃-K₂O-F). The important feature of this study is the induction of nucleation/crystallization in the base glass matrix on addition of Cr⁶⁺ content under annealing heat treatment (600 ± 10 °C) only. The melt-quenched glass is found to be amorphous, which in the presence of Cr⁶⁺ ions became crystalline with a predominant crystalline phase, Spinel (MgCr₂O₄). Microstructural experiment revealed the development of 200–500 nm crystallite particles in Cr⁶⁺-doped glass-ceramic matrix, and such type microstructure governed the mechanical properties. The machinability of the Cr-doped glass-ceramic was thereby higher compared to base alumino-silicate glass (ASG). From the nano-indentation experiment, the Young’s modulus was estimated 25(±10) GPa for base glass and increased to 894(±21) GPa for Cr-doped glass ceramics. Similarly, the microhardness for the base glass was 0.6(±0.5) GPa (nano-indentation measurements) and 3.63(±0.18) GPa (micro-indentation measurements). And that found increased to 8.4(±2.3) (nano-indentation measurements) and 3.94(±0.20) GPa (micro-indentation measurements) for Cr-containing glass ceramic.

One of Indonesia’s main characteristics of tourism development is maritime tourism, which is synonymous with archipelagic countries. The diversity of maritime tourism offered by Indonesia will never end, so it needs to be considered more carefully and used relevantly to create sustainable tourism in Indonesia that provides broad benefits for the country. Many maritime tourism locations in Indonesia are beautiful but require more active promotion. The level of security and terrorism issues are a requirement that the government must consider. The novelty of this research describes the potential ecotourism development in the town of Makassar that stakeholders should consider in the formation of tourism policy. The research locations are in Makassar City, Samalona Island, Langkai Island, and Lanjukang Island. Ecotourism developed in the coastal areas of Makassar City, especially in Samalona, Lanjukang, and Langkai Islands, produces superior objects that collaborate elements of nature and society as the main attraction in the long term. Therefore, local governments need to strengthen monitoring of regional geopolitical developments in order to avoid security and terrorism problems that might cause inconvenience to tourists.

E-commerce is increasingly developing as a platform large and small companies use to carry out online transactions with consumers. However, the development of e-commerce is also fraught with new environmental problems. Various problems occur, such as data leaks and fraud in buying and selling transactions. This research aims to deepen the study of the e-commerce environment from the perspective of local policymakers, and this research completes a study on the analysis of e-commerce problems and solutions from the perspective of policy actors. The development of e-commerce still has an unsafe environment; the potential for fraud and data leakage is still significant, and a government response is needed, such as creating new regulations or revising existing regulations. This research uses qualitative analysis with a content analysis approach and national online news media as research data and information sources. Nvivo 12 Plus software was used to identify problems and solutions offered by actors in their narratives in the media. The results of this research show that data leaks and e-commerce have the potential to threaten the country’s resilience, conventional businesses are threatened with closure, and policymakers are shifting responsibility for overcoming e-commerce problems. Current regulations still need to be made appropriately to overcome e-commerce problems.

Today, diffusion-weighted MRI is an important, complementary sequence in an MRI of the abdomen, especially in oncological questions, but also in inflammatory diseases. The following paper deals with the technical basics and shows typical indications and findings as well as the value of the method in the diagnosis of parenchymatous upper abdominal organs and the gastrointestinal tract.

Overwhelming studies unanimously agreed that preservation of the environment is a central climax in the discourse of green banking. There is a growing interest in exploring green banking practices for fostering financial inclusion, economic growth and sustainable development as part of Vision 2030 in Saudi Arabia. There are insufficient studies that examine this in the context of Saudi Arabia. This study aims at exploring the potential of green banking in order to attain sustainable banking and financial inclusion in achieving vision 2030in the country. Qualitative content analysis is used as a methodology of the study. Data were gathered through different sources such as: Web of Science (WOS), related journals, newspapers, published references, research papers, library sources and environmental organizations reports. It is indicated that green banking initiatives can be instrumental in fostering sustainable economic and environmental development in the Kingdom. The paper highlighted various activities of green banking such as: renewable and clean energy, financing green agriculture/food security, high-quality infrastructure among others. Nonetheless, some impediments to the green banking practices such as: risks facing green banks, poor quality of financial services among others are also mentioned in this paper. The paper proffers solutions to the challenges impeding green banking practices. In conclusion, the financial and banking industries in Saudi Arabia has been proving reform of the sector through greening economy. It is there suggested that the stakeholders and policymakers should provide efficient and effective technical, operational legal frameworks for enhancing green economy in achieving Vision 2030 in the country.