Atomic interaction between mediator protein of human prostate cancer (PHPC) and Fe/C720 Buckyballs-Statin is important for medical science. For the first time, we use molecular dynamics (MD) approach based on Newton’s formalism to describe the destruction of PHPC via Fe/C720 Buckyballs-Statin with atomic accuracy. In this work, the atomic interaction of PHPC and Fe/C720 Buckyballs-Statin introduced via equilibrium molecular dynamics approach. In this method, each PHPC and Fe/C720 Buckyballs-Statin is defined by C, H, Cl, N, O, P, S, and Fe elements and contrived by universal force field (UFF) and DREIDING force-field to introduce their time evolution. The results of our studies regarding the dynamical behavior of these atom-base compounds have been reported by calculating the Potential energy, center of mass (COM) position, diffusion ratio and volume of defined systems. The estimated values for these quantities show the attraction force between Buckyball-based structure and protein sample, which COM distance of these samples changes from 10.27 Å to 2.96 Å after 10 ns. Physically, these interactions causing the destruction of the PHPC. Numerically, the volume of this biostructure enlarged from 665,276 Å3 to 737,143 Å3 by MD time passing. This finding reported for the first time which can be considered by the pharmaceutical industry. Simulations indicated the volume of the PHPC increases by Fe/C720 Buckyballs-Statin diffusion into this compound. By enlarging this quantity (diffusion coefficient), the atomic stability of PHPC decreases and protein destruction procedure fulfilled.

In the dynamic landscape of modern education, the integration of vocational education and intelligent technologies has emerged as a pivotal strategy for fostering lifelong learning. This essay delves into the synergistic relationship between vocational education and the era of intelligent education, highlighting their collective potential to empower individuals with skills that transcend traditional boundaries.

The central government of China has intensively guided regional integration and policy coordination towards the development of digital governance in the last ten years. The Guangdong-Hong Kong-Macao Greater Bay was one of the most important regions of China expected to accelerate regional development through policy coordination and establishment of digital infrastructures. This article adopted the method of content analysis to explore the policy transitions of digital governance in the Greater Bay including policy contents (in terms of policy objectives and instruments) and policy networks. Based on our empirical analysis, we found that top-down guidance from the central government did not necessarily generate regional coordination. Different governments of the same region could start policy coordination from shared policy objectives and policy instruments and establish innovative governance frameworks to achieve consensus. Therefore, regional coordination could be fulfilled.

The conversion of the energy supply to renewable sources (wind, photovoltaics) will increase the volatility in electricity generation in the future. In order to ensure a balanced power balance in the power grid, storage is required - not only for a short time, but also seasonally. The bidirectional coupling of existing energy infrastructure with the power grid can help here by using the electricity in electrolysis systems to produce hydrogen. The hydrogen can be mixed with natural gas in the existing infrastructure (gas storage, pipelines) to a limited extent or converted directly to methane in a gas-catalytic reaction, methanation, with carbon dioxide and/or carbon monoxide. By using the natural gas infrastructure, the electricity grids are relieved and renewable energies can also be stored over long periods of time. Another advantage of this technology, known as “Power-to-Gas”, is that the methane produced in this way represents a sink for CO₂ emissions, as it replaces fossil sources and CO₂ is thus fed into a closed cycle.

Research in the field of Power-to-Gas technology is currently addressing technological advances both in the field of electrolysis and for the subsequent methanation, in particular to reduce investment costs. In the field of methanation, load-flexible processes are to be developed that are adapted to the fluctuating supply of hydrogen. The profitability of the Power-to-Gas process chain can be increased through synergistic integration into existing industrial processes. For example, an integrated smelting works offers a promising infrastructural environment, since, on the one hand, process gases containing carbon are produced in large quantities and, on the other hand, the oxygen as a by-product from the water electrolysis can be used directly. Such concepts suggest an economic application of Power-to-Gas technology in the near future.

Horticulture is a widespread activity in family farming in the Transamazonian region—Pará, with emphasis on production aimed at the family’s own consumption. The lettuce cultivar Vanda (Lactuca sativa L.) represents a significant part of this production, which prioritizes the use of internal labor. The main objective of this work was to evaluate the development of lettuce CV Vanda grown in beds using organic compost and chemical fertilization (NPK). The criteria considered to evaluate this performance were: Root system development, plant height and total fresh mass production. The best averages in relation to root development occurred in the plots cultivated with organic compost in the proportion of 5 kg/m², due to its characteristics as a fertilizer and soil conditioner. The cultivation with the use of NPK provided the best averages in relation to the production of total fresh mass and plant height, results that were mainly attributed to the extra supply of nitrogen in the covering fertilization, which consisted in the addition of 10 g urea per square meter via soil. Statistical analysis showed no statistically significant difference regarding plant height for both treatments. And in relation to root development, the difference was statistically significant.

Magnetite magnetic nanoparticles (MNP) exhibit superparamagnetic behavior, which gives them important properties such as low coercive field, easy superficial modification and acceptable magnetization levels. This makes them useful in separation techniques. However, few studies have experimented with the interactions of MNP with magnetic fields. Therefore, the aim of this research was to study the influence of an oscillating magnetic field (OMF) on polymeric monolithic columns with vinylated magnetic nanoparticles (VMNP) for capillary liquid chromatography (cLC). For this purpose, MNP were synthesized by coprecipitation of iron salts. The preparation of polymeric monolithic columns was performed by copolymerization and aggregation of VMNP. Taking advantage of the magnetic properties of MNP, the influence of parameters such as resonance frequency, intensity and exposure time of a OMF applied to the synthesized columns was studied. As a result, a better separation of a sample according to the measured parameters was obtained, so that a column resolution (R_s) of 1.35 was achieved. The morphological properties of the columns were evaluated by scanning electron microscopy (SEM). The results of the chromatographic properties revealed that the best separation of the alkylbenzenes sample occurs under conditions of 5.5 kHz and 10 min of exposure in the OMF. This study constitutes a first application in chromatographic separation techniques for future research in nanotechnology.