In recent years, the pathological diagnosis of glomerular diseases typically involves the study of glomerular his-to pathology by specialized pathologists, who analyze tissue sections stained with Periodic Acid-Schiff (PAS) to assess tissue and cellular abnormalities. In recent years, the rapid development of generative adversarial networks composed of generators and discriminators has led to further developments in image colorization tasks. In this paper, we present a generative adversarial network by Spectral Normalization colorization designed for color restoration of grayscale images depicting glomerular cell tissue elements. The network consists of two structures: the generator and the discriminator. The generator incorporates a U-shaped decoder and encoder network to extract feature information from input images, extract features from Lab color space images, and predict color distribution. The discriminator network is responsible for optimizing the generated colorized images by comparing them with real stained images. On the Human Biomolecular Atlas Program (HubMAP)—Hacking the Kidney FTU segmentation challenge dataset, we achieved a peak signal-to-noise ratio of 29.802 dB, along with high structural similarity results as other colorization methods. This colorization method offers an approach to add color to grayscale images of glomerular cell tissue units. It facilitates the observation of physiological information in pathological images by doctors and patients, enabling better pathological-assisted diagnosis of certain kidney diseases.
In the era of rapid information technology development, artificial intelligence (AI) and virtual reality (VR) technologies have gradually infiltrated the field of university English teaching, brought significant applications and impacted to English language learning in listening, speaking, writing, translation, and personalized learning. AI plays a vital role as an auxiliary teaching method in university English instruction, and the integration of VR technology further enhances teaching efficiency. This research will propose relevant recommendations to provide theoretical references for university English education in the age of AI, while also offering insights and guidance to educators in the education industry during the informatization reform of education.
This article analyzes the use and limitations of nonmonetary contract incentives in managing third-party accountability in human services. In-depth case studies of residential care homes for the elderly and integrated family service centers, two contrasting contracting contexts, were conducted in Hong Kong. These two programs vary in service programmability and service interdependency. In-depth interviews with 17 managers of 48 Residential Care Homes for the Elderly (RCHEs) and 20 managers of 10 Integrated Family Service Centers (IFSCs) were conducted. Interviews with the managers show that when service programmability was high and service interdependency was low, nonmonetary contract incentives such as opportunities for self-actualization professionally or reputation were effective in improving service quality from nonprofit and for-profit contractors. When service programmability was low and service interdependency was high, despite that only nonprofit organizations were contracted, many frontline service managers reported that professional accountability was undermined by ambiguous service scope, performance emphasis on case turnover, risk shift from public service units and a lack of formal accountability relationships between service units in the service network. The findings shed light on the limitations of nonmonetary contract incentives.
Cancer is the 3rd leading cause of death globally, and the countries with low-to-middle income account for most cancer cases. The current diagnostic tools, including imaging, molecular detection, and immune histochemistry (IHC), have intrinsic limitations, such as poor accuracy. However, researchers have been working to improve anti-cancer treatment using different drug delivery systems (DDS) to target tumor cells more precisely. Current advances, however, are enough to meet the growing call for more efficient drug delivery systems, but the adverse effects of these systems are a major problem. Nanorobots are typically controlled devices made up of nanometric component assemblies that can interact with and even diffuse the cellular membrane due to their small size, offering a direct channel to the cellular level. The nanorobots improve treatment efficiency by performing advanced biomedical therapies using minimally invasive operations. Chemotherapy’s harsh side effects and untargeted drug distribution necessitate new cancer treatment trials. The nanorobots are currently designed to recognize 12 different types of cancer cells. Nanorobots are an emerging field of nanotechnology with nanoscale dimensions and are predictable to work at an atomic, molecular, and cellular level. Nanorobots to date are under the line of investigation, but some primary molecular models of these medically programmable machines have been tested. This review on nanorobots presents the various aspects allied, i.e., introduction, history, ideal characteristics, approaches in nanorobots, basis for the development, tool kit recognition and retrieval from the body, and application considering diagnosis and treatment.
Idiomatic phrase are one of the lexical units.Many second-language learners showing great enthusiasm for using idiomatic expressions because of the rich cultural factors inherent in them and the vibrant,hilarious language that is close to life-like.However, the idiomatic terms are so complicated that they frequently cause foreign learners to struggle with learning and comprehending Chinese.With its own advantages, the idea of lexical chunks has the potential to be a game changer in the teaching of idiomatic.
In most studies on hydroclimatic variability and trend, the notion of change point detection analysis of time series data has not been considered. Understanding the system is crucial for managing water resources sustainably in the future since it denotes a change in the status quo. If this happened, it is difficult to distinguish the time series data’s rising or falling tendencies in various areas when we look at the trend analysis alone. This study’s primary goal was to describe, quantify, and confirm the homogeneity and change point detection of hydroclimatic variables, including mean annual, seasonal, and monthly rainfall, air temperature, and streamflow. The method was employed using the four-homogeneity test, i.e., Pettitt’s test, Buishand’s test, standard normal homogeneity test, and von Neumann ratio test at 5% significance level. In order to choose the homogenous stations, the test outputs were divided into three categories: “useful”, “doubtful”, and “suspect”. The results showed that most of the stations for annual rainfall and air temperature were homogenous. It is found that 68.8% and 56.2% of the air temperature and rainfall stations respectively, were classified as useful. Whereas, the streamflow stations were classified 100% as useful. Overall, the change point detection analyses timings were found at monthly, seasonal, and annual time scales. In the rainfall time series, no annual change points were detected. In the air temperature time series except at Edagahamus station, all stations experienced an increasing change point while the streamflow time series experienced a decreasing change point except at Agulai and Genfel hydro stations. While alterations in streamflow time series without a noticeable change in rainfall time series recommend the change is caused by variables besides rainfall. Most probably the observed abrupt alterations in streamflow could result from alterations in catchment characteristics like the subbasin’s land use and cover. These research findings offered important details on the homogeneity and change point detection of the research area’s air temperature, rainfall, and streamflow necessary for the planers, decision-makers, hydrologists, and engineers for a better water allocation strategy, impact assessment and trend analyses.
Copyright © by EnPress Publisher. All rights reserved.