South Korea has experienced rapid economic development since the 1960s. However, pronounced regional disparities have concurrently emerged. Amid the escalating regional inequalities and persistent demographic challenges characterized by low fertility rates, regional decline has become a pressing issue. Therefore, the feasibility of expanding transportation networks as a countermeasure to regional decline has been proposed. This study utilizes the synthetic control method and spatial difference-in-differences methodologies to assess the impact of the 2017 opening of Seoul–Yangyang Expressway on economic development and population inflow within Hongcheon-gun, Inje-gun, and Yangyang-gun. The purpose of this study is to evaluate the effectiveness of highway development as a policy instrument to mitigate regional decline. Findings from the synthetic control method analysis suggest a positive impact of the opening of the expressway on Hongcheon-gun’s Gross Regional Domestic Product (GRDP) in 2018, as well as Yangyang-gun’s net migration rates from 2017 to 2019. Conversely, the spatial difference-in-differences analysis, designed to identify spillover effects, reveals negative impacts of the highway on the GRDP and net migration rates of adjacent regions. Consequently, although targeted transportation infrastructure development in key non Seoul Metropolitan cities may contribute to ameliorating regional imbalances, results indicate that such measures alone are unlikely to suffice in attracting population to small- and medium-sized cities outside the Seoul Metropolitan Area.

Hospital waste containing antibiotics is toxic to the ecosystem. Ciprofloxacin is one of the essential, widely used antibiotics and is often detected in water bodies and soil. It is vital to treat these medical wastes, which urge new research towards waste management practices in hospital environments themselves. Ultimately minimizes its impact in the ecosystem and prevents the spread of antibiotic resistance. The present study highlights the decomposition of ciprofloxacin using nano-catalytic ZnO materials by reactive oxygen species (ROS) process. The most effective process to treat the residual antibiotics by the photocatalytic degradation mechanism is explored in this paper. The traditional co-precipitation method was used to prepare zinc oxide nanomaterials. The characterization methods, X-Ray diffraction analysis (XRD), Fourier Transform infrared spectroscopy (FTIR), Ulraviolet-Visible spectroscopy (UV-Vis), Scanning Electron microscopy (SEM) and X-Ray photoelectron spectroscopy (XPS) have done to improve the photocatalytic activity of ZnO materials. The mitigation of ciprofloxacin catalyzed by ZnO nano-photocatalyst was described by pseudo-first-order kinetics and chemical oxygen demand (COD) analysis. In addition, ZnO materials help to prevent bacterial species, S. aureus and E. coli, growth in the environment. This work provides some new insights towards ciprofloxacin degradation in efficient ways.

Protein- and peptide-based medications are recognized for their effectiveness and lower toxicity compared to chemical-based drugs, making them promising therapeutic agents. However, their application has been limited by numerous delivery challenges. Polymeric nanostructures have emerged as effective tools for protein delivery due to their versatility and customizability. Polymers’ inherent adaptability makes them ideal for meeting the specific demands of protein-delivery systems. Various strategies have been employed, such as enzyme inhibitors, absorption enhancers, mucoadhesive polymers, and chemical modifications of proteins or peptides. This study explores the hurdles associated with protein and peptide transport, the use of polymeric nanocarriers (both natural and synthetic) to overcome these challenges, and the techniques for fabricating and characterizing nanoparticles.

In older adults with disabilities, muscle weakness reduces mobility and causes postural issues. Electrical muscle stimulation (EMS) training is effective for increasing strength by inducing involuntary skeletal muscle contractions. Thus, this study aimed to examine changes in lumbar movement, muscle activity during walking, and maximum muscle strength of lower-limb joints based on an 8-week EMS exercise program for older adults with physical disabilities. Sixteen older adults (aged 56–78 years) with physical disabilities were selected and randomly assigned to either the exercise group (EG, n = 8) or the control group (CG, n = 8). EG participants were instructed to wear EMS suits and participate in an elastic band and bare-body exercise program, whereas CG participants performed the exercise program without the EMS suits. Lumbar range of motion (ROM), body circumference, partial volume, maximum muscle strength, and muscle activity were measured. Statistical analysis was performed using SPSS 28.0 for Windows, with the critical value of α = 0.05. Compared to CG participants, EG participants had a superior ROM, body volume, partial volume, maximum muscle strength (knee joints), and muscle activity while walking. These positive outcomes highlight the efficacy of combining EMS with an exercise program for strength and rehabilitation training in older adults with physical disabilities.

The aim of this study is to determine how bank diversification affects bank stability. To this end, it examines data of 136 commercial banks operating in 14 MENA (Middle East and North Africa) countries observed from 2005 to 2021, using the System Generalized Method of Moments (GMM) panel data regression analysis. The selected countries are Bahrain, Egypt, Jordan, Kuwait, Oman, Qatar, Saudi Arabia, Morocco, Lebanon, Algeria, Tunisia, Iran, Iraq, and the United Arab Emirates. The main results point to the enhancing effect of income diversification on bank stability. Our results underline the “Bright Side” of banking income diversification in the MENA region. However, this stabilizing income diversification effect is not always maintainable. The results also point to a non-linear relationship between interest/non-interest income and financial stability, suggesting that higher diversification reduces risk. We use a dynamic panel threshold model to determine income diversification thresholds that stabilize banks in the MENA region.