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Enhancing diabetic retinopathy and glaucoma diagnosis through efficient retinal vessel segmentation and disease classification
Asadi Srinivasulu
S Venkata Achuta Rao
Clement Varaprasad Karu
G Sreenivasulu
G N V Vibhav Reddy
Imaging and Radiation Research 2025, 8(2); https://doi.org/10.24294/irr3313
Submitted:16 Nov 2023
Accepted:19 Nov 2024
Published:29 Dec 2025
Abstract

This research underscores the importance of enhancing the early detection of diabetic retinopathy and glaucoma, two prominent culprits behind vision loss. Typically, retinal diseases lurk without symptoms until they inflict severe vision impairment, underscoring the critical need for early identification. The research is centered on the potential of leveraging fundus images, which offer invaluable insights by analyzing various attributes of retinal blood vessels, such as their length, width, tortuosity, and branching patterns. The conventional practice of manually segmenting retinal vessels by medical professionals is both intricate and time-consuming, demanding specialized expertise. This approach, reliant on pathologists, grapples with limitations related to scalability and accessibility. To surmount these challenges, the research introduces an automated solution employing computer vision. It conducts an evaluation of diverse retinal vessel segmentation and classification methods, including machine learning, filtering-based, and model-based techniques. Robust performance assessments, involving metrics like the true positive rate, true negative rate, and accuracy, facilitate a comprehensive comparison of these methodologies. The ultimate goal of this research is to create more efficient and accessible diagnostic tools, consequently enhancing the early detection of eye diseases through automated retinal vessel segmentation and classification. This endeavor combines the capabilities of computer vision and deep learning to pioneer new benchmarks in the realm of biomedical imaging, thereby addressing the pressing issues surrounding eye disease diagnosis.


© 2025 by the EnPress Publisher, LLC. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.

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