Cysteine is one of the body’s essential amino acids to build proteins. For the early diagnosis of a number of diseases and biological issues, L-cysteine (L-Cys) is essential. Our study presents an electrochemical sensor that detects L-cysteine by immobilizing the horseradish peroxidase (HRP) enzyme on a reduced graphene oxide (GCE) modified glassy carbon electrode. The morphologies and chemical compositions of synthesized materials were examined using Fourier transform infrared spectroscopy (FTIR) and field-emission scanning electron microscopy (FESEM). The modified electrode’s electrochemical behavior was investigated using cyclic voltammetry (CV). Cyclic voltammetry demonstrated HRP/rGO/GCE has better electrocatalytic activity than bare GCE in the oxidation of L-cysteine oxidation in a solution of acetate buffer. The electrochemical sensor had a broad linear range of 0 µM to 1 mM, a 0.32 µM detection limit, and a sensitivity of 6.08 μA μM−1 cm−2. The developed sensor was successfully used for the L-cysteine detection in a real blood sample with good results.
Gender inequality is a structural social problem, associated with history, culture, education, religion and politics, this difficulty occurs in all social institutions due to the heterogeneity of the structure in the sexual division of labor, socioeconomic inequality, inclusion and inequity in participation in the public space between men and women. Public policies and attitudes towards gender equality in Peruvian university students were analyzed according to socio-academic variables. A descriptive-comparative study, with a quantitative approach, and not experimental cross-sectional, involved 776 university students from a public and a private university in Peru, intentionally selected. Adaptive attitudes (57.9%) were found to tend to be sexist; Likewise, in the study dimensions, the same trend was found in the sociocultural and relational levels, while in the personal dimension students develop sexist attitudes (62.4%). It is concluded, attitudes towards gender equality are sexist reproduction that is influenced by the sociocultural environment of the family, this situation occurs to a greater extent in men, while female students present attitudes of equality in greater intensity to seek equity in the distribution of roles.
Artificial intelligence (AI) has rapidly evolved, transforming industries and addressing societal challenges across sectors such as healthcare and education. This study provides a state-of-the-art overview of AI research up to 2023 through a bibliometric analysis of the 50 most influential papers, identified using Scopus citation metrics. The selected works, averaging 74 citations each, encompass original research, reviews, and editorials, demonstrating a diversity of impactful contributions. Over 300 contributing authors and significant international collaboration highlight AI’s global and multidisciplinary nature. Our analysis reveals that research is concentrated in core journals, as described by Bradford’s Law, with leading contributions from institutions in the United States, China, Canada, the United Kingdom, and Australia. Trends in authorship underscore the growing role of generative AI systems in advancing knowledge dissemination. The findings illustrate AI’s transformative potential in practical applications, such as enabling early disease detection and precision medicine in healthcare and fostering adaptive learning systems and accessibility in education. By examining the dynamics of collaboration, geographic productivity, and institutional influence, this study sheds light on the innovation drivers shaping the AI field. The results emphasize the need for responsible AI development to maximize societal benefits and mitigate risks. This research provides an evidence-based understanding of AI’s progress and sets the stage for future advancements. It aims to inform stakeholders and contribute to the ongoing scientific discourse, offering insights into AI’s impact at a time of unprecedented global interest and investment.
Intellectual property (IP) is a crucial issue as it directly impacts economic growth. This research analyzed the dynamic governance reconstruction within Indonesia’s Ministry of Law and Human Rights aimed at transforming it into a world-class Intellectual Property Office (IPO). A systematic review of 20 articles was conducted. The results showed that the Directorate General of Intellectual Property (DGIP) under the Ministry has numerous opportunities to become a world-class IPO. Protecting intellectual works through IP rights enhances inclusiveness, such as ensuring operational freedoms. The Indonesian government is employing dynamic governance methods to contextualize and implement bureaucratic reforms. However, there is resistance to change as old habits conflict with the new order, posing a challenge to bureaucratic reform. Strategies to create a world-class IPO involve improving technology utilization and fostering innovation. The protection of IP rights has widened inclusivity by enabling operational freedoms. Under dynamic governance, the bureaucracy is being restructured to be more context-aware and agile in its execution. Yet, ingrained practices resist reform, creating friction with the new systems being instituted. Initiatives to elevate the DGIP include technological modernization and promoting a more innovative culture. By reviewing these aspects systematically, the research provides insights into the opportunities and challenges in transforming Indonesia’s IP office into a world-class institution capable of driving economic growth through robust IP governance.
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