Fog computing (FC) has been presented as a modern distributed technology that will overcome the different issues that Cloud computing faces and provide many services. It brings computation and data storage closer to data resources such as sensors, cameras, and mobile devices. The fog computing paradigm is instrumental in scenarios where low latency, real-time processing, and high bandwidth are critical, such as in smart cities, industrial IoT, and autonomous vehicles. However, the distributed nature of fog computing introduces complexities in managing and predicting the execution time of tasks across heterogeneous devices with varying computational capabilities. Neural network models have demonstrated exceptional capability in prediction tasks because of their capacity to extract insightful patterns from data. Neural networks can capture non-linear interactions and provide precise predictions in various fields by using numerous layers of linked nodes. In addition, choosing the right inputs is essential to forecasting the correct value since neural network models rely on the data fed into the network to make predictions. The scheduler may choose the appropriate resource and schedule for practical resource usage and decreased make-span based on the expected value. In this paper, we suggest a model Neural Network model for fog computing task time execution prediction and an input assessment of the Interpretive Structural Modeling (ISM) technique. The proposed model showed a 23.9% reduction in MRE compared to other methods in the state-of-arts.
The fast-growing field of nanotheranostics is revolutionizing cancer treatment by allowing for precise diagnosis and targeted therapy at the cellular and molecular levels. These nanoscale platforms provide considerable benefits in oncology, including improved disease and therapy specificity, lower systemic toxicity, and real-time monitoring of therapeutic outcomes. However, nanoparticles' complicated interactions with biological systems, notably the immune system, present significant obstacles for clinical translation. While certain nanoparticles can elicit favorable anti-tumor immune responses, others cause immunotoxicity, including complement activation-related pseudoallergy (CARPA), cytokine storms, chronic inflammation, and organ damage. Traditional toxicity evaluation approaches are frequently time-consuming, expensive, and insufficient to capture these intricate nanoparticle-biological interactions. Artificial intelligence (AI) and machine learning (ML) have emerged as transformational solutions to these problems. This paper summarizes current achievements in nanotheranostics for cancer, delves into the causes of nanoparticle-induced immunotoxicity, and demonstrates how AI/ML may help anticipate and create safer nanoparticles. Integrating AI/ML with modern computational approaches allows for the detection of potentially dangerous nanoparticle qualities, guides the optimization of physicochemical features, and speeds up the development of immune-compatible nanotheranostics suited to individual patients. The combination of nanotechnology with AI/ML has the potential to completely realize the therapeutic promise of nanotheranostics while assuring patient safety in the age of precision medicine.
In this review are developed insights from the current research work to develop the concept of functional materials. This is understood as real modified substrates for varied applications. So, functional and modified substrates focused on nanoarchitectures, microcapsules, and devices for new nanotechnologies highlighting life sciences applications were revised. In this context, different types of concepts to proofs of concepts of new materials are shown to develop desired functions. Thus, it was shown that varied chemicals, emitters, pharmacophores, and controlled nano-chemistry were used for the design of nanoplatforms to further increase the sizes of materials. In this regard, the prototyping of materials was discussed, affording how to afford the challenge in the design and fabrication of new materials. Thus, the concept of optical active materials and the generation of a targeted signal through the substrate were developed. Moreover, advanced concepts were introduced, such as the multimodal energy approach by tuning optical coupling from molecules to the nanoscale within complex matter composites. These approaches were based on the confinement of specific optical matter, considering molecular spectroscopics and nano-optics, from where the new concept nominated as metamaterials was generated. In this manner, fundamental and applied research by the design of hierarchical bottom-up materials, controlling molecules towards nanoplatforms and modified substrates, was proposed. Therefore, varied accurate length scales and dimensions were controlled. Finally, it showed proofs of concepts and applications of implantable, portable, and wearable devices from cutting-edge knowledge to the next generation of devices and miniaturized instrumentation.
Open-source software (OSS) has emerged as a transformative tool whose implementation has the potential to modernise many libraries around the world in the digital age. OSS is a type of software which permits its users to inspect, share, modify, and enhance through its freely accessed source code. The accessibility and openness of the source code permits users to manipulate, change, and improve the way in which a piece of software, program, or application works. OSS solutions therefore provide cost-effective alternatives that enable libraries to enhance their technological infrastructure without being constrained by proprietary systems. Hence, many countries have initiated and formulated policies and legislative frameworks to support the implementation and use of OSS library solutions such as DSpace, Alfresco, and Greenstone. The purpose of the study reported on was to investigate the leveraging of OSS to modernise public libraries in South Africa. Content analysis was adopted as the research methodology for this qualitative study, which was based on a literature review integrating insights from the researchers’ experiences with the use of OSS in libraries The findings of the study reveal that the use of OSS has the potential to modernise public libraries, especially those located outside cities or urban areas. These libraries are often less well equipped with the necessary technology infrastructure to meet the demands of the digital age, such as online books and open access materials. The study culminated in an OSS framework that may be implemented to modernise public libraries. This framework may help public libraries to integrate OSS solutions and further allow users access to digital services.
Rising fuel prices can affect driver behavior and thus the number of accidents, which is a key road safety issue. The aim of this paper was to assess and quantify the relationship between fuel prices (FP) and the number of road accidents in Europe. Content analysis of statistics from the countries was used to collect data, which were examined using Ramsey resets and Poisson distributions and then processed using negative binomial regression (NB), cluster analysis and visualization using contour plots. The results show that in Germany and Poland there is a statistically significant low negative correlation between fuel price and the number of traffic accidents, while in the Czech Republic and Denmark the relationship is weaker and statistically insignificant. In Iceland, no significant correlation was found. The contribution of this paper is to provide important insights that can be used in the development of transport policies and regulations to improve road safety. The main limitations include the difficulty of data collection, as many countries do not publish detailed statistics, and the low number of accidents in Iceland, which makes it impossible to perform a robust analysis for this country and may cause generalization of the results.
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